Management of injuries caused by cryptococcus neoformans-contaminated needles

Arturo Casadevall; Jean Mukherjee; Rui Rong Yuan; John Perfect

doi:10.1093/clinids/19.5.951

Management of injuries caused by cryptococcus neoformans-contaminated needles

Arturo Casadevall, Jean Mukherjee, Rui Rong Yuan, John Perfect

Research output: Contribution to journal › Article › peer-review

22 Scopus citations

Abstract

This report describes four skin-puncture accidents with needles that were heavily contaminated with Cryptococcus neoformans. In one accident, delayed administration of antifungal drugs resulted in a granuloma of the finger. In the other three accidents, no skin infection followed immediate prophylaxis with oral fluconazole. Our experience suggests that early therapy with fluconazole is a reasonable means of managing skin injuries caused by instruments contaminated with viable C. neoformans.

Original language	English (US)
Pages (from-to)	951-953
Number of pages	3
Journal	Clinical Infectious Diseases
Volume	19
Issue number	5
DOIs	https://doi.org/10.1093/clinids/19.5.951
State	Published - Nov 1994
Externally published	Yes

ASJC Scopus subject areas

Microbiology (medical)
Infectious Diseases

Access to Document

10.1093/clinids/19.5.951

Cite this

@article{a2d5b19564c442658e44a1271aecada7,

title = "Management of injuries caused by cryptococcus neoformans-contaminated needles",

abstract = "This report describes four skin-puncture accidents with needles that were heavily contaminated with Cryptococcus neoformans. In one accident, delayed administration of antifungal drugs resulted in a granuloma of the finger. In the other three accidents, no skin infection followed immediate prophylaxis with oral fluconazole. Our experience suggests that early therapy with fluconazole is a reasonable means of managing skin injuries caused by instruments contaminated with viable C. neoformans.",

author = "Arturo Casadevall and Jean Mukherjee and Yuan, {Rui Rong} and John Perfect",

note = "Funding Information: Received 20 January 1994; revised 15 March 1994. Financial support: A. C. was supported by a James S. McDonnell Scholar Award and NIH grants A133774 and All 3342. J. M. and R. R. Y. were supported by NIH grants CA-39839 and CA-13330-30. Reprints or correspondence: Dr. Arturo Casadevall, Department ofMedicine, Ullman 1219, 1300 Morris Park Avenue, Bronx, New York 10461.",

year = "1994",

month = nov,

doi = "10.1093/clinids/19.5.951",

language = "English (US)",

volume = "19",

pages = "951--953",

journal = "Clinical Infectious Diseases",

issn = "1058-4838",

publisher = "Oxford University Press",

number = "5",

}

TY - JOUR

T1 - Management of injuries caused by cryptococcus neoformans-contaminated needles

AU - Casadevall, Arturo

AU - Mukherjee, Jean

AU - Yuan, Rui Rong

AU - Perfect, John

N1 - Funding Information: Received 20 January 1994; revised 15 March 1994. Financial support: A. C. was supported by a James S. McDonnell Scholar Award and NIH grants A133774 and All 3342. J. M. and R. R. Y. were supported by NIH grants CA-39839 and CA-13330-30. Reprints or correspondence: Dr. Arturo Casadevall, Department ofMedicine, Ullman 1219, 1300 Morris Park Avenue, Bronx, New York 10461.

PY - 1994/11

Y1 - 1994/11

N2 - This report describes four skin-puncture accidents with needles that were heavily contaminated with Cryptococcus neoformans. In one accident, delayed administration of antifungal drugs resulted in a granuloma of the finger. In the other three accidents, no skin infection followed immediate prophylaxis with oral fluconazole. Our experience suggests that early therapy with fluconazole is a reasonable means of managing skin injuries caused by instruments contaminated with viable C. neoformans.

AB - This report describes four skin-puncture accidents with needles that were heavily contaminated with Cryptococcus neoformans. In one accident, delayed administration of antifungal drugs resulted in a granuloma of the finger. In the other three accidents, no skin infection followed immediate prophylaxis with oral fluconazole. Our experience suggests that early therapy with fluconazole is a reasonable means of managing skin injuries caused by instruments contaminated with viable C. neoformans.

UR - http://www.scopus.com/inward/record.url?scp=0028075813&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0028075813&partnerID=8YFLogxK

U2 - 10.1093/clinids/19.5.951

DO - 10.1093/clinids/19.5.951

M3 - Article

C2 - 7893887

AN - SCOPUS:0028075813

SN - 1058-4838

VL - 19

SP - 951

EP - 953

JO - Clinical Infectious Diseases

JF - Clinical Infectious Diseases

IS - 5

ER -

Management of injuries caused by cryptococcus neoformans-contaminated needles

Abstract

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this