Cervical spine fractures in osteogenesis imperfecta are rare. The purpose of this article is to describe the successful outcomes of the nonoperative and operative treatment of C2 pars fracture and operative treatment of C7 compression fracture in two children with osteogenesis imperfecta. Patient 1, a 22-month-old female, had a C2 pars fracture managed nonoperatively with a cervical orthosis. Patient 2, a 15-year-old male, had concurrent C2 pars and C7 compression fractures; the C2 pars fractures were treated operatively via a posterior approach and open reduction and internal fixation, and the C7 compression fracture was treated via a C7 corpectomy, iliac crest strut autograft, and anterior plating from C6 to T1. Patient 1 had delayed union but complete healing at latest follow-up (31 months postpresentation). At latest follow-up, patient 2 remained asymptomatic.
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