Management of atlantoaxial metastases with posterior occipitocervical stabilization

Daryl R. Fourney, Julie E. York, Zvi R. Cohen, Dima Suki, Laurence D. Rhines, Ziya L. Gokaslan

Research output: Contribution to journalArticle

Abstract

Object. The treatment of atlantoaxial spinal metastases is complicated by the region's unique biomechanical and anatomical characteristics. Patients most frequently present with pain secondary to instability; neurological deficits are rare. Recently, some authors have performed anterior approaches (transoral or extraoral) for resection of upper cervical metastases. The authors review their experience with a surgical strategy that emphasizes posterior stabilization of the spine and avoidance of poorly tolerated external orthoses such as the rigid cervical collar or halo vest. Methods. The authors performed a retrospective review of 19 consecutively treated patients with C-1 or C-2 metastases who underwent surgery at The University of Texas M. D. Anderson Cancer Center between 1994 and 2001. Visual analog pain scores were reduced at 1 and 3 months (p <0.005, Wilcoxon signed-rank test); however, evaluation of pain at 6 months and 1 year was limited by the remaining number of surviving patients. Analgesic medication consumption was unchanged. There were no cases of neurological decline or sudden death secondary to residual or recurrent atlantoaxial disease during the follow-up period. One patient underwent revision of hardware at 11 months. The mean follow-up period was 8 months (range 1-32 months). Median survival determined by Kaplan-Meier analysis was 6.1 months (95% confidence interval 2.99-9.21). Conclusions. Occipitocervical stabilization provided durable pain relief and preservation of ambulatory status over the remaining life span of patients. Because of the palliative goals of surgery, the authors have not found an indication for anterior-approach tumor resection in these patients. Successful stabilization obviates the need for an external orthosis.

Original languageEnglish (US)
Pages (from-to)165-170
Number of pages6
JournalJournal of Neurosurgery
Volume98
Issue number2 SUPPL.
StatePublished - Mar 1 2003

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Neoplasm Metastasis
Pain
Orthotic Devices
Kaplan-Meier Estimate
Nonparametric Statistics
Sudden Death
Palliative Care
Analgesics
Neoplasms
Spine
Confidence Intervals
Survival
Therapeutics

Keywords

  • Atlantoaxial stabilization
  • Cervical spine
  • Metastasis
  • Palliation

ASJC Scopus subject areas

  • Clinical Neurology
  • Neuroscience(all)

Cite this

Fourney, D. R., York, J. E., Cohen, Z. R., Suki, D., Rhines, L. D., & Gokaslan, Z. L. (2003). Management of atlantoaxial metastases with posterior occipitocervical stabilization. Journal of Neurosurgery, 98(2 SUPPL.), 165-170.

Management of atlantoaxial metastases with posterior occipitocervical stabilization. / Fourney, Daryl R.; York, Julie E.; Cohen, Zvi R.; Suki, Dima; Rhines, Laurence D.; Gokaslan, Ziya L.

In: Journal of Neurosurgery, Vol. 98, No. 2 SUPPL., 01.03.2003, p. 165-170.

Research output: Contribution to journalArticle

Fourney, DR, York, JE, Cohen, ZR, Suki, D, Rhines, LD & Gokaslan, ZL 2003, 'Management of atlantoaxial metastases with posterior occipitocervical stabilization', Journal of Neurosurgery, vol. 98, no. 2 SUPPL., pp. 165-170.
Fourney DR, York JE, Cohen ZR, Suki D, Rhines LD, Gokaslan ZL. Management of atlantoaxial metastases with posterior occipitocervical stabilization. Journal of Neurosurgery. 2003 Mar 1;98(2 SUPPL.):165-170.
Fourney, Daryl R. ; York, Julie E. ; Cohen, Zvi R. ; Suki, Dima ; Rhines, Laurence D. ; Gokaslan, Ziya L. / Management of atlantoaxial metastases with posterior occipitocervical stabilization. In: Journal of Neurosurgery. 2003 ; Vol. 98, No. 2 SUPPL. pp. 165-170.
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