Management and Outcomes of Cardiogenic Shock in Cardiac ICUs With Versus Without Shock Teams

Critical Care Cardiology Trials Network Investigators

Research output: Contribution to journalArticlepeer-review


Background: Single-center studies suggest that implementation of multidisciplinary cardiogenic shock (CS) teams is associated with improved CS survival. Objectives: The aim was to characterize practice patterns and outcomes in the management of CS across multiple centers with versus without shock teams. Methods: The Critical Care Cardiology Trials Network is a multicenter network of cardiac intensive care units (CICUs) in North America. All consecutive medical admissions to each CICU (n = 24) were captured during annual 2-month collection periods (2017-2019; n = 6,872). Shock management and CICU mortality among centers with versus without shock teams were compared using inverse probability weighting. Results: Ten of the 24 centers had shock teams. Among 1,242 CS admissions, 44% were at shock team centers. The groups were well-balanced with respect to demographics, shock etiology, Sequential Organ Failure Assessment score, biochemical markers of end organ dysfunction, and invasive hemodynamics. Centers with shock teams used more pulmonary artery catheters (60% vs 49%; adjusted odds ratio [OR]: 1.86; 95% CI: 1.47-2.35; P < 0.001), less overall mechanical circulatory support (MCS) (35% vs 43%; adjusted OR: 0.74; 95% CI: 0.59-0.95; P = 0.016), and more advanced types of MCS (53% vs 43% of all MCS; adjusted OR: 1.73; 95% CI: 1.19-2.51; P = 0.005) rather than intra-aortic balloon pumps. The presence of a shock team was independently associated with lower CICU mortality (23% vs 29%; adjusted OR: 0.72; 95% CI: 0.55-0.94; P = 0.016). Conclusions: In this multicenter observational study, centers with shock teams were more likely to obtain invasive hemodynamics, use advanced types of MCS, and have lower risk-adjusted mortality. A standardized multidisciplinary shock team approach may improve outcomes in CS.

Original languageEnglish (US)
Pages (from-to)1309-1317
Number of pages9
JournalJournal of the American College of Cardiology
Issue number13
StatePublished - Sep 28 2021


  • cardiac intensive care unit
  • cardiogenic shock
  • mechanical circulatory support
  • pulmonary artery catheter
  • shock team

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine


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