Mammographic densities and risk of breast cancer

A. F. Saftlas, R. N. Hoover, L. A. Brinton, Moyses Szklo, D. R. Olson, M. Salane, J. N. Wolfe

Research output: Contribution to journalArticle

Abstract

To determine the relation of mammographic densities to subsequent breast cancer risk, a case-control study was undertaken using prediagnostic mammograms of screening program participants. Mammograms of cases (n = 266) and controls (n = 301) were blindly assessed for mammographic densities, which were measured by planimetry. The odds of breast cancer increased steadily with increasing breast density (test for trend, P <0.0001). Breast cancer odds was 1.7 for densities between 5% and 24.9%, 2.5 for 25% through 44.9%, 3.8 for 45% through 64%, and 4.3 for densities of 65% and greater (referent =

Original languageEnglish (US)
Pages (from-to)2833-2838
Number of pages6
JournalCancer
Volume67
Issue number11
StatePublished - 1991
Externally publishedYes

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Breast Neoplasms
Case-Control Studies
Breast Density

ASJC Scopus subject areas

  • Cancer Research
  • Oncology

Cite this

Saftlas, A. F., Hoover, R. N., Brinton, L. A., Szklo, M., Olson, D. R., Salane, M., & Wolfe, J. N. (1991). Mammographic densities and risk of breast cancer. Cancer, 67(11), 2833-2838.

Mammographic densities and risk of breast cancer. / Saftlas, A. F.; Hoover, R. N.; Brinton, L. A.; Szklo, Moyses; Olson, D. R.; Salane, M.; Wolfe, J. N.

In: Cancer, Vol. 67, No. 11, 1991, p. 2833-2838.

Research output: Contribution to journalArticle

Saftlas, AF, Hoover, RN, Brinton, LA, Szklo, M, Olson, DR, Salane, M & Wolfe, JN 1991, 'Mammographic densities and risk of breast cancer', Cancer, vol. 67, no. 11, pp. 2833-2838.
Saftlas AF, Hoover RN, Brinton LA, Szklo M, Olson DR, Salane M et al. Mammographic densities and risk of breast cancer. Cancer. 1991;67(11):2833-2838.
Saftlas, A. F. ; Hoover, R. N. ; Brinton, L. A. ; Szklo, Moyses ; Olson, D. R. ; Salane, M. ; Wolfe, J. N. / Mammographic densities and risk of breast cancer. In: Cancer. 1991 ; Vol. 67, No. 11. pp. 2833-2838.
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