Tumori maligni delle ghiandole salivari della laringe: Un’unica review istituzionale

Translated title of the contribution: Malignant salivary gland tumours of the larynx: A single institution review

S. Karatayli-Ozgursoy, J. A. Bishop, Alexander Tell Hillel, Lee M Akst, Simon R Best

Research output: Contribution to journalArticle

Abstract

Malignant salivary gland tumours of the larynx are very rare, with limited reports of clinical outcomes. We present the decade-long experience of a single institution. A 10-year retrospective chart review of a tertiary head and neck cancer centre was performed. Index patients were identified from a review of a pathology database, and reviewed by a head and neck pathologist. Patient demographics, presenting signs and symptoms, treatment modalities and clinical outcomes were extracted from electronic medical records. Six patients were included, with an age range of 44 to 69. All six had malignant laryngeal salivary gland tumours. Pathologies included: three adenoid cystic carcinoma (2 supraglottic, 1 subglottic), one mucoepidermoid carcinoma (supraglottic), one epithelial-myoepithelial carcinoma (supraglottic) and one adenocarcinoma (transglottic). All were treated with surgery (2 endolaryngeal, 4 open) and five of six with the addition of adjuvant therapy (4 radiotherapy, 1 concurrent chemoradiation). One patient had smoking history; no patients had significant alcohol history. With 4.5 years of median follow-up, none of the patients has had recurrence or local/distant metastasis. Salivary gland tumours of the larynx present in mid to late-age, and can be successfully managed with a multi-modality approach, resulting in excellent local and regional control rates.

Original languageItalian
Pages (from-to)289-294
Number of pages6
JournalActa Otorhinolaryngologica Italica
Volume36
Issue number4
DOIs
StatePublished - Aug 1 2016

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Glandular and Epithelial Neoplasms
Larynx
History
Pathology
Mucoepidermoid Carcinoma
Adenoid Cystic Carcinoma
Electronic Health Records
Head and Neck Neoplasms
Signs and Symptoms
Adenocarcinoma
Neck
Radiotherapy
Smoking
Head
Alcohols
Demography
Databases
Neoplasm Metastasis
Carcinoma
Recurrence

Keywords

  • Cancer
  • Chemotherapy
  • Larynx
  • Partial laryngectomy
  • Salivary
  • Surgery

ASJC Scopus subject areas

  • Otorhinolaryngology

Cite this

Tumori maligni delle ghiandole salivari della laringe : Un’unica review istituzionale. / Karatayli-Ozgursoy, S.; Bishop, J. A.; Hillel, Alexander Tell; Akst, Lee M; Best, Simon R.

In: Acta Otorhinolaryngologica Italica, Vol. 36, No. 4, 01.08.2016, p. 289-294.

Research output: Contribution to journalArticle

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