Malignant fibrous histiocytoma of soft tissue with metaplastic bone and cartilage formation: A new radiologic sign

Howard D. Dorfman, Belur S. Bhagavan

Research output: Contribution to journalArticlepeer-review

Abstract

The presence of bone and cartilage in some cases of malignant fibrous histiocytoma of the soft tissue as a microscopic finding has been reported previously but little note has been taken of the radiologic manifestations of these tumor elements. A series of five such cases with sufficient metaplastic osseous and cartilaginous elements to produce roentgenographic evidence of their presence is reported here. An additional two cases showed only histologic evidence of bone or cartilage formation. The reactive ossification tends to be peripheral in location, involving the pseudocapsule of the sarcoma or its fibrous septa. In three there was a zoning pattern with peripheral or polar orientation, strongly suggesting the diagnosis of myositis ossificans. The latter was the diagnosis considered radiologically in four of the five cases. Malignant fibrous histiocytoma with reactive bone and cartilage must be considered in the differential diagnosis of soft tissue masses with calcific densities, particularly when these occur in tumors of the extremities.

Original languageEnglish (US)
Pages (from-to)145-150
Number of pages6
JournalSkeletal Radiology
Volume8
Issue number2
DOIs
StatePublished - May 1 1982

Keywords

  • Malignant fibrous histiocytoma
  • Myositis ossificans
  • Soft tissue
  • metaplastic bone and cartilage

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

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