Câncer em pacientes com HIV/AIDS atendidos em clínica ambulatorial em vitória, estado do espírito santo, Brasil

Translated title of the contribution: Malignancies in HIV/AIDS patients attending an outpatient clinic in vitória, state of Espírito santo, Brazil

Lauro Ferreira Da Silva Pinto Neto, Maria Da Conceição Milanez, Jonathan Eric Golub, Angelica Espinosa Barbosa Miranda

Research output: Contribution to journalArticlepeer-review

Abstract

Introduction: The present study investigated cancer prevalence and associated factors among HIV-infected individuals attending an AIDS outpatient clinic in Vitória, State of Espírito Santo, Brazil. Methods: A sectional study was conducted among HIV infected adults attending an AIDS outpatient clinic in Vitória, State of Espírito Santo, Brazil. Demographic, epidemiological and clinical data were abstracted from medical records, including cancer diagnoses; nadir and current CD4 cell count, HIV viral load, time on antiretroviral treatment (ART), type of ART and smoking status. Results: A total of 730 (91.3%) patients were included in the study. Median age was 44.0 [interquartile range (IQR): 35-50.3] years; median time since HIV diagnosis was 5.5 years (IQR: 2-10); 60% were male; and 59% were white. Thirty (4.1%) cases of cancer were identified of which 16 (53%) were AIDS defining cancers and 14 (47%) were non-AIDS defining malignancies. Patients diagnosed with cancer presented higher chance of being tobacco users [OR 2.2 (95% CI: 1.04-6.24)]; having nadir CD4 ≤200 cells/mm3 [OR 3.0 (95% CI: 1.19-7.81)] and higher lethality [OR 13, 3 (95% CI: 4, 57-38, 72)]. Conclusions: These results corroborate the importance of screening for and prevention of non-AIDS defining cancers focus in HIV-infected population, as these cancers presented with similar frequency as AIDS defining cancers.

Translated title of the contributionMalignancies in HIV/AIDS patients attending an outpatient clinic in vitória, state of Espírito santo, Brazil
Original languagePortuguese
Pages (from-to)687-690
Number of pages4
JournalRevista da Sociedade Brasileira de Medicina Tropical
Volume45
Issue number6
DOIs
StatePublished - Nov 2012

Keywords

  • Brazil
  • HIV/AIDS
  • Malignancies
  • Prevalence

ASJC Scopus subject areas

  • Parasitology
  • Microbiology (medical)
  • Infectious Diseases

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