Male circumcision and the risk of sexually transmitted infections and HIV in Rakai, Uganda

Ronald Gray, Jim Azire, David Serwadda, Noah Kiwanuka, Godfrey Kigozi, Bmohamed Kiddugavu, Fred Nalugoda, Xianbin Li, Maria Wawer

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Abstract

We assessed the prevalence of sexually transmitted infections (STIs) caused by gonorrhea, chlamydia, syphilis and herpes simplex virus 2, genital ulcer disease and discharge/dysuria, and the incidence of HIV in circumcised and uncircumcised men in a Ugandan cohort study. There were no significant differences in the prevalence of STIs or genitourinary symptoms, but HIV incidence was significantly lower in circumcised men. The preputial mucosa is probably an important target tissue for HIV, but not other STIs.

Original languageEnglish (US)
Pages (from-to)2428-2430
Number of pages3
JournalAIDS
Volume18
Issue number18
StatePublished - Dec 3 2004

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ASJC Scopus subject areas

  • Immunology and Allergy
  • Immunology
  • Infectious Diseases

Cite this

Gray, R., Azire, J., Serwadda, D., Kiwanuka, N., Kigozi, G., Kiddugavu, B., Nalugoda, F., Li, X., & Wawer, M. (2004). Male circumcision and the risk of sexually transmitted infections and HIV in Rakai, Uganda. AIDS, 18(18), 2428-2430.