TY - JOUR
T1 - Major electrocardiographic abnormalities in persons aged 65 years and older (the Cardiovascular Health Study)
AU - Furberg, Curt D.
AU - Manolio, Teri A.
AU - Psaty, Bruce M.
AU - Bild, Diane E.
AU - Borhani, Nemat O.
AU - Newman, Anne
AU - Tabatznik, Bernard
AU - Rautaharju, Pentti M.
N1 - Funding Information:
From the Department of Public Health Sciences, Bowman Gray School of Medicine, Winston-Salem, North Carolina; Division of Epidemiology and Clinical Applications, National Heart, Lung, and Blood Institute, Bethesda, Maryland; Departments of Medicine, Epidemiology and Health Services, University of Washington, Seattle, Washington; Departments of Internal Medicine and Community Health, School of Medicine, University of California, Davis, California; Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania; Departments of Medicine and Epidemiology, Johns Hopkins University, Baltimore, Maryland; and Epicore Center, Department of Medicine, University of Alberta, Edmonton, Alberta, Canada. This study was supported by contracts NOl-HC-85079, NOl-HC-85080, NOl-HC-85081, NOl-HC-85082, NOl-HC-85083, NOl-HC-85084, NOI-HC-85085 and NOl-HC-85086 from the National Heart, Lung, and Blood Institute, Bethesda, Maryland. Manuscript received September 6, 1991; revised manuscript received and accepted January 3, 1992.
Copyright:
Copyright 2014 Elsevier B.V., All rights reserved.
PY - 1992/5/15
Y1 - 1992/5/15
N2 - Electrocardiographic abnormalities are often found in older patients, but their prevalence in free-living elderly populations is not well-defined. In addition, the clinical significance of many of these abnormalities is uncertain. The prevalence of major electrocardiographic abnormalities was determined in 5,150 adults aged ≥65 years from the Cardiovascular Health Study - a study of risk factors for stroke and coronary heart disease in the elderly. Ventricular conduction defects, major Q/QS waves, left ventricular hypertrophy, isolated major ST-T-wave abnormalities, atrial fibrillation and first-degree atrioventricular block were collectively categorized as major electrocardiographic abnormalities. Prevalence of any major electrocardiographic abnormality was 29% in the entire cohort, 19% among 2,413 participants who reported no history of coronary artery disease or systemic hypertension, and 37% among 2,737 participants with a history of coronary artery disease or hypertension. Prevalence of major electrocardiographic abnormalities was higher in men than in women regardless of history, and tended to increase with age. Major Q/QS waves were found in 5.2%, and more than half were in those who did not report a previous myocardial infarction. Major electrocardiographic abnormalities are common in elderly men and women irrespective of the history of heart disease.
AB - Electrocardiographic abnormalities are often found in older patients, but their prevalence in free-living elderly populations is not well-defined. In addition, the clinical significance of many of these abnormalities is uncertain. The prevalence of major electrocardiographic abnormalities was determined in 5,150 adults aged ≥65 years from the Cardiovascular Health Study - a study of risk factors for stroke and coronary heart disease in the elderly. Ventricular conduction defects, major Q/QS waves, left ventricular hypertrophy, isolated major ST-T-wave abnormalities, atrial fibrillation and first-degree atrioventricular block were collectively categorized as major electrocardiographic abnormalities. Prevalence of any major electrocardiographic abnormality was 29% in the entire cohort, 19% among 2,413 participants who reported no history of coronary artery disease or systemic hypertension, and 37% among 2,737 participants with a history of coronary artery disease or hypertension. Prevalence of major electrocardiographic abnormalities was higher in men than in women regardless of history, and tended to increase with age. Major Q/QS waves were found in 5.2%, and more than half were in those who did not report a previous myocardial infarction. Major electrocardiographic abnormalities are common in elderly men and women irrespective of the history of heart disease.
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U2 - 10.1016/0002-9149(92)91231-R
DO - 10.1016/0002-9149(92)91231-R
M3 - Article
C2 - 1585868
AN - SCOPUS:0026684520
SN - 0002-9149
VL - 69
SP - 1329
EP - 1335
JO - The American journal of cardiology
JF - The American journal of cardiology
IS - 16
ER -