Major coat protein and single-stranded DNA binding protein of filamentous virus Pf3

D. G. Putterman, A. Casadevall, P. D. Boyle, H. L. Yang, B. Frangione, L. A. Day

Research output: Contribution to journalArticle

Abstract

The region of the Pf3 virus genome encoding its major coat protein and its single-stranded DNA binding protein is organized somewhat like the corresponding region of the fd (M13, f1) genome. Nevertheless, the major coat protein is unique among the major coat proteins of fd and the other filamentous phages studied in that it lacks a signal sequence and appears to be a direct translation product and in that it has fewer basic amino acid residues than its equivalent of DNA phosphates in the virion. These features are relevant to considerations of both protein insertion into membranes and DNA structure in filamentous viruses. The single-stranded DNA-binding protein also has a sequence that is different from the sequences of single-stranded DNA-binding proteins from other filamentous viruses.

Original languageEnglish (US)
Pages (from-to)699-703
Number of pages5
JournalProceedings of the National Academy of Sciences of the United States of America
Volume81
Issue number3 I
DOIs
StatePublished - 1984

ASJC Scopus subject areas

  • General

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