Magnetic resonance spectroscopy in major depressive disorder

Mona Mohamed, Ali Sibtain Farooq Sheikh

Research output: Contribution to journalArticle

Abstract

In this paper, we have collected and discussed the current literature on MRS/MRSI techniques used in cases of depression to help understand the pathophysiology of the disease. The literature search using National Institutes of Health’s PubMed database, Scopus, and Google Scholar, provided us with 71 peer-reviewed publications to look at the disease effects amongst adolescent children, adult as well as the elderly population. Metabolite changes in N-acetyl aspartate (NAA), choline (Cho), glutamate (Glu), and Gamma Aminobutyric Acid (GABA) are quite consistent in some brain regions among comparable studies, with a few inconsistencies noted due to the different study designs.

Original languageEnglish (US)
Pages (from-to)167-187
Number of pages21
JournalInternational Journal of Emergency Mental Health
Volume17
Issue number1
StatePublished - 2015

Fingerprint

Major Depressive Disorder
Magnetic Resonance Spectroscopy
Choline
PubMed
gamma-Aminobutyric Acid
Publications
Glutamic Acid
Databases
Depression
Brain
Population
N-acetylaspartate

Keywords

  • Brain metabolites
  • Depression
  • MRS

ASJC Scopus subject areas

  • Medicine(all)
  • Psychiatry and Mental health

Cite this

Magnetic resonance spectroscopy in major depressive disorder. / Mohamed, Mona; Sheikh, Ali Sibtain Farooq.

In: International Journal of Emergency Mental Health, Vol. 17, No. 1, 2015, p. 167-187.

Research output: Contribution to journalArticle

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