Magnetic resonance perfusion imaging in the study of language

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Abstract

This paper provides a brief review of various uses of magnetic resonance perfusion imaging in the investigation of brain/language relationships. The reviewed studies illustrate how perfusion imaging can reveal areas of brain where dysfunction due to low blood flow is associated with specific language deficits, and where restoration of blood flow to improve the tissue function results in recovery of those deficits. This sort of evidence helps to reveal areas of the brain that are essential to a particular language task. Other studies have provided clues regarding the mechanisms of early language recovery, or have shown how perfusion imaging can identify patients with chronic hypoperfusion due to cerebrovascular stenosis in whom the BOLD effect in fMRI may be absent or reduced in areas of neural activation.

Original languageEnglish (US)
Pages (from-to)165-175
Number of pages11
JournalBrain and Language
Volume102
Issue number2
DOIs
StatePublished - Aug 2007

Keywords

  • Aphasia
  • Magnetic resonance imaging
  • Perfusion-weighted
  • Stroke

ASJC Scopus subject areas

  • Language and Linguistics
  • Experimental and Cognitive Psychology
  • Linguistics and Language
  • Cognitive Neuroscience
  • Speech and Hearing

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