TY - JOUR
T1 - Magnetic resonance microscopy of mouse brain development.
AU - Mori, Susumu
AU - Zhang, Jiangyang
AU - Bulte, Jeff W.M.
PY - 2006
Y1 - 2006
N2 - Magnetic resonance imaging (MRI) is increasingly becoming an important tool to study anatomy of rodent brains. Compared with histology, it has clear advantages because the entire 3D object can be captured as an image nondestructively. However, low imaging resolution and a small number of available contrast mechanisms are two critical disadvantages. In this article, the future potential of magnetic resonance (MR) microimaging is discussed, with special emphasis on diffusion tensor microimaging as an effective contrast mechanism for the developing central nervous system.
AB - Magnetic resonance imaging (MRI) is increasingly becoming an important tool to study anatomy of rodent brains. Compared with histology, it has clear advantages because the entire 3D object can be captured as an image nondestructively. However, low imaging resolution and a small number of available contrast mechanisms are two critical disadvantages. In this article, the future potential of magnetic resonance (MR) microimaging is discussed, with special emphasis on diffusion tensor microimaging as an effective contrast mechanism for the developing central nervous system.
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U2 - 10.1385/1-59745-010-3:129
DO - 10.1385/1-59745-010-3:129
M3 - Review article
C2 - 16506420
AN - SCOPUS:33645221458
SN - 1543-1894
VL - 124
SP - 129
EP - 147
JO - Methods in Molecular Medicine
JF - Methods in Molecular Medicine
ER -