Magnetic resonance imaging in multiple sclerosis: Decreased signal in thalamus and putamen

Burton P. Drayer, Peter Burger, Barrie Hurwitz, Deborah Dawson, John Cain, Jackie Leong, Robert Herfkens, G. Allan Johnson

Research output: Contribution to journalArticle

Abstract

High‐field strength (1.5 Tesla) magnetic resonance imaging in 15 patients with multiple and extensive white‐matter lesions and clinically definite multiple sclerosis delineated a previously underscribed finding of abnormally Decemberreased signal intensity on T2‐weighted images in the thalamus and putamen. The Decemberreased signal intensity (preferential Decemberreased T2 relaxation time) is most likely to be related to abnormally increased iron accumulation causing local magnetic field heterogeneities.

Original languageEnglish (US)
Pages (from-to)546-550
Number of pages5
JournalAnnals of neurology
Volume22
Issue number4
DOIs
StatePublished - Oct 1987

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ASJC Scopus subject areas

  • Neurology
  • Clinical Neurology

Cite this

Drayer, B. P., Burger, P., Hurwitz, B., Dawson, D., Cain, J., Leong, J., Herfkens, R., & Allan Johnson, G. (1987). Magnetic resonance imaging in multiple sclerosis: Decreased signal in thalamus and putamen. Annals of neurology, 22(4), 546-550. https://doi.org/10.1002/ana.410220418