Magnetic resonance imaging in multiple sclerosis

Decreased signal in thalamus and putamen

B. P. Drayer, P. Burger, B. Hurwitz, D. Dawson, J. Cain, J. Leong, R. Herfkens, G. A. Johnson

Research output: Contribution to journalArticle

Abstract

High-field strength (1.5 Tesla) magnetic resonance imaging in 15 patients with multiple and extensive white-matter lesions and clinically definite multiple sclerosis delineated a previously undescribed finding of abnormally decreased signal intensity on T2-weighted images in the thalamus and putamen. The decreased signal intensity (preferential decreased T2 relaxation time) is most likely to be related to abnormally increased iron accumulation causing local magnetic field heterogeneities.

Original languageEnglish (US)
Pages (from-to)546-550
Number of pages5
JournalAnnals of Neurology
Volume22
Issue number4
StatePublished - 1987
Externally publishedYes

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Putamen
Magnetic Fields
Thalamus
Multiple Sclerosis
Iron
Magnetic Resonance Imaging
White Matter

ASJC Scopus subject areas

  • Neuroscience(all)

Cite this

Drayer, B. P., Burger, P., Hurwitz, B., Dawson, D., Cain, J., Leong, J., ... Johnson, G. A. (1987). Magnetic resonance imaging in multiple sclerosis: Decreased signal in thalamus and putamen. Annals of Neurology, 22(4), 546-550.

Magnetic resonance imaging in multiple sclerosis : Decreased signal in thalamus and putamen. / Drayer, B. P.; Burger, P.; Hurwitz, B.; Dawson, D.; Cain, J.; Leong, J.; Herfkens, R.; Johnson, G. A.

In: Annals of Neurology, Vol. 22, No. 4, 1987, p. 546-550.

Research output: Contribution to journalArticle

Drayer, BP, Burger, P, Hurwitz, B, Dawson, D, Cain, J, Leong, J, Herfkens, R & Johnson, GA 1987, 'Magnetic resonance imaging in multiple sclerosis: Decreased signal in thalamus and putamen', Annals of Neurology, vol. 22, no. 4, pp. 546-550.
Drayer BP, Burger P, Hurwitz B, Dawson D, Cain J, Leong J et al. Magnetic resonance imaging in multiple sclerosis: Decreased signal in thalamus and putamen. Annals of Neurology. 1987;22(4):546-550.
Drayer, B. P. ; Burger, P. ; Hurwitz, B. ; Dawson, D. ; Cain, J. ; Leong, J. ; Herfkens, R. ; Johnson, G. A. / Magnetic resonance imaging in multiple sclerosis : Decreased signal in thalamus and putamen. In: Annals of Neurology. 1987 ; Vol. 22, No. 4. pp. 546-550.
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