Magnetic resonance imaging findings in patients meeting Task Force criteria for arrhythmogenic right ventricular dysplasia

Harikrishna Tandri, Hugh Calkins, Khurram Nasir, Chandra Bomma, Ernesto Castillo, Julie Rutberg, Crystal Tichnell, João A.C. Lima, David A. Bluemke

Research output: Contribution to journalArticle

Abstract

Introduction: Magnet resonance imaging (MRI) findings in patients meeting Task Force criteria for the diagnosis of arrhythmogenic right ventricular dysplasia (ARVD) have not been systematically described. We report qualitative and quantitative MRI findings in ARVD using state-of-the-art MRI. Methods and Results: MRI was performed on 12 patients with ARVD who were prospectively diagnosed using the Task Force criteria. The imaging protocol included breath-hold double inversion recovery spin-echo and gradient-echo images. Ventricular volumes and dimensions were compared to 10 age- and sex-matched normal volunteers. High intramyocardial T1 signal similar to fat signal was observed in 9 (75%) of the 12 patients and in none of the controls. Right ventricular (RV) hypertrophy was seen in 5 (42%) patients, trabecular disarray in 7 (59%), and wall thinning in 3 (25%). Both the RV end-diastolic diameter and the outflow tract area were significantly higher in ARVD patients compared to controls (51.2 vs 43.2 mm, P < 0.01; and 14.5 vs 9.3 cm2, P < 0.01, respectively). ARVD patients had a higher RV end-diastolic volume index and lower RV ejection fraction compared with controls (127.4 vs 87.5, P < 0.01; and 41.6% vs 57%, P < 0.01, respectively). Conclusion: High intramyocardial T1 signal indicative of fat is seen in a high percentage (75%) of patients who meet the Task Force criteria for ARVD. Trabecular disarray is seen more frequently than wall thinning and aneurysms. RV dimensions and volumes differ significantly in ARVD compared to controls, indicating a role for quantitative evaluation in the diagnosis of ARVD.

Original languageEnglish (US)
Pages (from-to)476-482
Number of pages7
JournalJournal of cardiovascular electrophysiology
Volume14
Issue number5
DOIs
StatePublished - May 1 2003

Keywords

  • Arrhythmia
  • Cardiomyopathy
  • Diagnosis
  • Magnetic resonance imaging
  • Right ventricle

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine
  • Physiology (medical)

Fingerprint Dive into the research topics of 'Magnetic resonance imaging findings in patients meeting Task Force criteria for arrhythmogenic right ventricular dysplasia'. Together they form a unique fingerprint.

  • Cite this