Magnetic resonance abnormalities and cardiovascular disease in older adults the cardiovascular health study

Teri A. Manolio, Richard A. Kronmal, Gregory L. Burke, Virginia Poirier, Daniel H. O’Leary, Julius M. Gardin, Linda P Fried, Earl P. Steinberg, R. Nick Bryan

Research output: Contribution to journalArticle

Abstract

Background and PurposeCerebral magnetic resonance imaging often detects abnormalities whose significance is unknown. The prevalence and correlates of findings such as ventricular enlargement, sulcal widening, and increased white matter signal intensity were examined in 303 men and women aged 65 to 95 years participating in a multicenter study of cardiovascular disease. MethodsCerebral magnetic resonance imaging was performed and interpreted according to a standard protocol, and findings were correlated with measures of cardiovascular disease and its risk factors. ResultsMeasures of cerebral atrophy increased with age and were greater in men than in women (each P

Original languageEnglish (US)
Pages (from-to)318-327
Number of pages10
JournalStroke
Volume25
Issue number2
StatePublished - 1994

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Cardiovascular Diseases
Magnetic Resonance Spectroscopy
Magnetic Resonance Imaging
Health
Multicenter Studies
Atrophy
White Matter

Keywords

  • Epidemiology
  • Leukoencephalopathy
  • Magnetic resonance imaging
  • Risk factors

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine
  • Clinical Neurology
  • Advanced and Specialized Nursing
  • Neuroscience(all)

Cite this

Manolio, T. A., Kronmal, R. A., Burke, G. L., Poirier, V., O’Leary, D. H., Gardin, J. M., ... Bryan, R. N. (1994). Magnetic resonance abnormalities and cardiovascular disease in older adults the cardiovascular health study. Stroke, 25(2), 318-327.

Magnetic resonance abnormalities and cardiovascular disease in older adults the cardiovascular health study. / Manolio, Teri A.; Kronmal, Richard A.; Burke, Gregory L.; Poirier, Virginia; O’Leary, Daniel H.; Gardin, Julius M.; Fried, Linda P; Steinberg, Earl P.; Bryan, R. Nick.

In: Stroke, Vol. 25, No. 2, 1994, p. 318-327.

Research output: Contribution to journalArticle

Manolio, TA, Kronmal, RA, Burke, GL, Poirier, V, O’Leary, DH, Gardin, JM, Fried, LP, Steinberg, EP & Bryan, RN 1994, 'Magnetic resonance abnormalities and cardiovascular disease in older adults the cardiovascular health study', Stroke, vol. 25, no. 2, pp. 318-327.
Manolio TA, Kronmal RA, Burke GL, Poirier V, O’Leary DH, Gardin JM et al. Magnetic resonance abnormalities and cardiovascular disease in older adults the cardiovascular health study. Stroke. 1994;25(2):318-327.
Manolio, Teri A. ; Kronmal, Richard A. ; Burke, Gregory L. ; Poirier, Virginia ; O’Leary, Daniel H. ; Gardin, Julius M. ; Fried, Linda P ; Steinberg, Earl P. ; Bryan, R. Nick. / Magnetic resonance abnormalities and cardiovascular disease in older adults the cardiovascular health study. In: Stroke. 1994 ; Vol. 25, No. 2. pp. 318-327.
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