Abstract
Background: The aim of this study was to compare the efficacy of spectral-domain optical coherence tomography (SD-OCT) and fluorescein angiography (FA) in the guidance of macular laser photocoagulation for diabetic macular edema. Methods: This was a prospective interventional clinical comparative pilot study. Forty eyes from 24 consecutive patients with diabetic macular edema were allocated to receive laser pho- tocoagulation guided by SD-OCT or FA. Best-corrected visual acuity (BCVA), central macular thickness, and retinal volume were assessed at baseline and two months after treatment. Results: Subjects treated using FA-guided laser improved BCVA from the logarithm of the minimum angle of resolution (logMAR) 0.52 ± 0.2 to 0.37 ± 0.2 (P, 0.001), and decreased mean central macular thickness from 397.25 ± 139.1 to 333.50 ± 105.7 μm (P<0.001) and retinal volume from 12.61 ± 1.6 to 10.94 ± 1.4 mm3 (P<0.001). Subjects treated using SD-OCT guided laser had improved BCVA from 0.48 ± 0.2 to 0.33 ± 0.2 logMAR (P<0.001), and decreased mean central macular thickness from 425.90 ± 149.6 to 353.4 ± 140 μm (P<0.001) and retinal volume from 12.38 ± 2.1 to 11.53 ± 1.1 mm3 (P<0.001). No significant differences between the groups were found in two-month BCVA (P = 0.505), two-month central macular thickness (P = 0.660), or two-month retinal volume (P = 0.582). Conclusion: The short-term results of this pilot study suggest that SD-OCT is a safe and effective technique and could be considered as a valid alternative to FA in the guidance of macular laser photocoagulation treatment for diabetic macular edema.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 613-617 |
| Number of pages | 5 |
| Journal | Clinical Ophthalmology |
| Volume | 5 |
| Issue number | 1 |
| DOIs | |
| State | Published - 2011 |
| Externally published | Yes |
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Keywords
- Diabetic macular edema
- Fluorescein angiography
- Macular laser photocoagulation
- Spectral-domain optical coherence tomography
ASJC Scopus subject areas
- Ophthalmology
Cite this
Macular laser photocoagulation guided by spectral-domain optical coherence tomography versus fluorescein angiography for diabetic macular edema. / Gallego-Pinazo, Roberto; Suelves-Cogollos, Ana Marina; Dolz-Marco, Rosa; Arevalo, J Fernando; García-Delpech, Salvador; Luis Mullor, J.; Díaz-Llopis, Manuel.
In: Clinical Ophthalmology, Vol. 5, No. 1, 2011, p. 613-617.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Macular laser photocoagulation guided by spectral-domain optical coherence tomography versus fluorescein angiography for diabetic macular edema
AU - Gallego-Pinazo, Roberto
AU - Suelves-Cogollos, Ana Marina
AU - Dolz-Marco, Rosa
AU - Arevalo, J Fernando
AU - García-Delpech, Salvador
AU - Luis Mullor, J.
AU - Díaz-Llopis, Manuel
PY - 2011
Y1 - 2011
N2 - Background: The aim of this study was to compare the efficacy of spectral-domain optical coherence tomography (SD-OCT) and fluorescein angiography (FA) in the guidance of macular laser photocoagulation for diabetic macular edema. Methods: This was a prospective interventional clinical comparative pilot study. Forty eyes from 24 consecutive patients with diabetic macular edema were allocated to receive laser pho- tocoagulation guided by SD-OCT or FA. Best-corrected visual acuity (BCVA), central macular thickness, and retinal volume were assessed at baseline and two months after treatment. Results: Subjects treated using FA-guided laser improved BCVA from the logarithm of the minimum angle of resolution (logMAR) 0.52 ± 0.2 to 0.37 ± 0.2 (P, 0.001), and decreased mean central macular thickness from 397.25 ± 139.1 to 333.50 ± 105.7 μm (P<0.001) and retinal volume from 12.61 ± 1.6 to 10.94 ± 1.4 mm3 (P<0.001). Subjects treated using SD-OCT guided laser had improved BCVA from 0.48 ± 0.2 to 0.33 ± 0.2 logMAR (P<0.001), and decreased mean central macular thickness from 425.90 ± 149.6 to 353.4 ± 140 μm (P<0.001) and retinal volume from 12.38 ± 2.1 to 11.53 ± 1.1 mm3 (P<0.001). No significant differences between the groups were found in two-month BCVA (P = 0.505), two-month central macular thickness (P = 0.660), or two-month retinal volume (P = 0.582). Conclusion: The short-term results of this pilot study suggest that SD-OCT is a safe and effective technique and could be considered as a valid alternative to FA in the guidance of macular laser photocoagulation treatment for diabetic macular edema.
AB - Background: The aim of this study was to compare the efficacy of spectral-domain optical coherence tomography (SD-OCT) and fluorescein angiography (FA) in the guidance of macular laser photocoagulation for diabetic macular edema. Methods: This was a prospective interventional clinical comparative pilot study. Forty eyes from 24 consecutive patients with diabetic macular edema were allocated to receive laser pho- tocoagulation guided by SD-OCT or FA. Best-corrected visual acuity (BCVA), central macular thickness, and retinal volume were assessed at baseline and two months after treatment. Results: Subjects treated using FA-guided laser improved BCVA from the logarithm of the minimum angle of resolution (logMAR) 0.52 ± 0.2 to 0.37 ± 0.2 (P, 0.001), and decreased mean central macular thickness from 397.25 ± 139.1 to 333.50 ± 105.7 μm (P<0.001) and retinal volume from 12.61 ± 1.6 to 10.94 ± 1.4 mm3 (P<0.001). Subjects treated using SD-OCT guided laser had improved BCVA from 0.48 ± 0.2 to 0.33 ± 0.2 logMAR (P<0.001), and decreased mean central macular thickness from 425.90 ± 149.6 to 353.4 ± 140 μm (P<0.001) and retinal volume from 12.38 ± 2.1 to 11.53 ± 1.1 mm3 (P<0.001). No significant differences between the groups were found in two-month BCVA (P = 0.505), two-month central macular thickness (P = 0.660), or two-month retinal volume (P = 0.582). Conclusion: The short-term results of this pilot study suggest that SD-OCT is a safe and effective technique and could be considered as a valid alternative to FA in the guidance of macular laser photocoagulation treatment for diabetic macular edema.
KW - Diabetic macular edema
KW - Fluorescein angiography
KW - Macular laser photocoagulation
KW - Spectral-domain optical coherence tomography
UR - http://www.scopus.com/inward/record.url?scp=79957472466&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=79957472466&partnerID=8YFLogxK
U2 - 10.2147/OPTH.S16833
DO - 10.2147/OPTH.S16833
M3 - Article
VL - 5
SP - 613
EP - 617
JO - Clinical Ophthalmology
JF - Clinical Ophthalmology
SN - 1177-5467
IS - 1
ER -