Macular Infarction After Endophthalmitis Treated With Vitrectomy and Intravitreal Gentamicin

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We encountered two cases of macular infarction that occurred after vitrectomy performed for mild endophthalmitis, which, on culture, yielded Staphylococcus epidermidis. At the end of each vitrectomy, 0.4 mg of gentamicin, 1.0 mg of cefazolin, and 0.32 mg of dexamethasone were injected into the vitreous cavity. We are concerned that the macular lesion was a retinal toxic effect of gentamicin because of the recent description of similar lesions occurring after the inadvertent intraocular injection of massive doses of this drug.

Original languageEnglish (US)
Pages (from-to)367-371
Number of pages5
JournalArchives of Ophthalmology
Issue number3
Publication statusPublished - 1986
Externally publishedYes


ASJC Scopus subject areas

  • Ophthalmology

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