TY - JOUR
T1 - Macular Infarction After Endophthalmitis Treated With Vitrectomy and Intravitreal Gentamicin
AU - Conway, Brian P.
AU - Campochiaro, Peter A.
PY - 1986/3
Y1 - 1986/3
N2 - We encountered two cases of macular infarction that occurred after vitrectomy performed for mild endophthalmitis, which, on culture, yielded Staphylococcus epidermidis. At the end of each vitrectomy, 0.4 mg of gentamicin, 1.0 mg of cefazolin, and 0.32 mg of dexamethasone were injected into the vitreous cavity. We are concerned that the macular lesion was a retinal toxic effect of gentamicin because of the recent description of similar lesions occurring after the inadvertent intraocular injection of massive doses of this drug.
AB - We encountered two cases of macular infarction that occurred after vitrectomy performed for mild endophthalmitis, which, on culture, yielded Staphylococcus epidermidis. At the end of each vitrectomy, 0.4 mg of gentamicin, 1.0 mg of cefazolin, and 0.32 mg of dexamethasone were injected into the vitreous cavity. We are concerned that the macular lesion was a retinal toxic effect of gentamicin because of the recent description of similar lesions occurring after the inadvertent intraocular injection of massive doses of this drug.
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U2 - 10.1001/archopht.1986.01050150067028
DO - 10.1001/archopht.1986.01050150067028
M3 - Article
C2 - 3485422
AN - SCOPUS:0022578330
SN - 0003-9950
VL - 104
SP - 367
EP - 371
JO - Archives of ophthalmology
JF - Archives of ophthalmology
IS - 3
ER -