Macular full-thickness and lamellar holes in association with type 2 idiopathic macular telangiectasia

P. Charbel Issa, H. P N Scholl, A. Gaudric, P. Massin, A. E. Kreiger, S. Schwartz, F. G. Holz

Research output: Contribution to journalArticle

Abstract

Purpose: To describe patients with full-thickness macular holes (FTMHs) and lamellar macular holes (LMHs) in association with type 2 idiopathic macular telangiectasia (type 2 IMT). Methods: Six patients with either FTMH or LMH and type 2 IMT were evaluated by means of optical coherence tomography (OCT) imaging, funduscopy, and fluorescein angiography. Results: The age of the examined patients ranged from 57 to 70 years (mean 62.5±5.2), and best-corrected visual acuity of the affected eyes ranged from 20/50 to 20/200 (mean 20/100). All eyes showed macular abnormalities typical for nonproliferative type 2 IMT except for one eye with a proliferative disease stage. Three patients had an FTMH, one presenting with bilateral FTMH, and three had an LMH on OCT. In all cases of FTMH, the macular holes did not have elevated margins. Surgery was performed in two patients with a FTHM without subsequent functional improvement. Conclusions: The altered foveal anatomy with progressive atrophic changes within the neurosensory retina in type 2 IMT may predispose to the development of FTMH and LMH. Type 2 IMT should be considered in the differential diagnosis in patients presenting with macular holes. The association between the two may reflect alternative pathogenetic mechanisms in the development of macular holes.

Original languageEnglish (US)
Pages (from-to)435-441
Number of pages7
JournalEye (London, England)
Volume23
Issue number2
DOIs
StatePublished - 2009
Externally publishedYes

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Telangiectasis
Retinal Perforations
Optical Coherence Tomography
Fluorescein Angiography
Visual Acuity
Retina
Anatomy

Keywords

  • Full-thickness macular hole
  • Idiopathic macular telangiectasia
  • Idiopathic parafoveolar telangiectasis
  • Lamellar macular hole
  • Optical coherence tomography

ASJC Scopus subject areas

  • Ophthalmology
  • Medicine(all)

Cite this

Charbel Issa, P., Scholl, H. P. N., Gaudric, A., Massin, P., Kreiger, A. E., Schwartz, S., & Holz, F. G. (2009). Macular full-thickness and lamellar holes in association with type 2 idiopathic macular telangiectasia. Eye (London, England), 23(2), 435-441. https://doi.org/10.1038/sj.eye.6703003

Macular full-thickness and lamellar holes in association with type 2 idiopathic macular telangiectasia. / Charbel Issa, P.; Scholl, H. P N; Gaudric, A.; Massin, P.; Kreiger, A. E.; Schwartz, S.; Holz, F. G.

In: Eye (London, England), Vol. 23, No. 2, 2009, p. 435-441.

Research output: Contribution to journalArticle

Charbel Issa, P, Scholl, HPN, Gaudric, A, Massin, P, Kreiger, AE, Schwartz, S & Holz, FG 2009, 'Macular full-thickness and lamellar holes in association with type 2 idiopathic macular telangiectasia', Eye (London, England), vol. 23, no. 2, pp. 435-441. https://doi.org/10.1038/sj.eye.6703003
Charbel Issa, P. ; Scholl, H. P N ; Gaudric, A. ; Massin, P. ; Kreiger, A. E. ; Schwartz, S. ; Holz, F. G. / Macular full-thickness and lamellar holes in association with type 2 idiopathic macular telangiectasia. In: Eye (London, England). 2009 ; Vol. 23, No. 2. pp. 435-441.
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