Abstract
Background: Accurate evaluation of the biological behavior of Gastrointestinal stromal tumor and careful selection of patients with a high risk for tumor recurrence are necessary. In the present study, we analyzed prognostic factors in patients with GIST. Patients and Methods: A total of 214 patients who had undergone curative resection of a localized primary gastric GIST without adjuvant therapy were enrolled in this retrospective study. Prognostic factors were analyzed. The growth pattern was classified as intramural, endoluminal, exoluminal, or mixed- type. Results: On univariate and multivariate analyses, recurrence was predicted by exoluminal or mixed-type (hazard ratio [HR]=3.7, p=0.043), tumor size of >3.5 cm (HR=7.1, p=0.01), and mitotic rate of >5/50 high-power fields (HR=7.9, p
Original language | English (US) |
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Pages (from-to) | 4267-4274 |
Number of pages | 8 |
Journal | Anticancer Research |
Volume | 34 |
Issue number | 8 |
State | Published - Aug 1 2014 |
Externally published | Yes |
Keywords
- Gastrointestinal stromal tumor
- GIST
- Prognosis
- Risk of recurrence
ASJC Scopus subject areas
- Cancer Research
- Oncology