Macrophage diversity in cardiac inflammation: A review

Jobert G. Barin, Noel R. Rose, Daniela Čiháková

Research output: Contribution to journalReview articlepeer-review

Abstract

Cardiac inflammatory disease represents a significant public health burden, and interesting questions of immunopathologic science and clinical inquiry. Novel insights into the diverse programming and functions within the macrophage lineages in recent years have yielded a view of these cells as dynamic effectors and regulators of immunity, host defense, and inflammatory disease. In this review, we examine and discuss recent investigations into the complex participation of mononuclear phagocytic cells in the pathology of animal models of myocarditis.

Original languageEnglish (US)
Pages (from-to)468-475
Number of pages8
JournalImmunobiology
Volume217
Issue number5
DOIs
StatePublished - May 2012

Keywords

  • Autoimmunity
  • Macrophage
  • Monocyte
  • Myocarditis

ASJC Scopus subject areas

  • Immunology and Allergy
  • Immunology
  • Hematology

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