Abstract
To assess the potential value of magnetic resonance (MR) imaging in monitoring disease status, 34 patients with residual masses underwent MR imaging at sequential intervals. Patterns of signal intensity suggestive of active and inactive residual disease were compared to changes in tumor size. The signal intensity pattern was suggestive of persistent disease in 18 patients, even though tumor size was stable or decreased. Three of these patterns, seen within 6 months of initiation of therapy, were due to necrosis or inflammation. The MR imaging assessment of inactive disease was confirmed in 15 of the remaining 16 patients. In no case was an increase in tumor size seen in conjunction with a decrease in signal intensity. Because tumor size and signal intensity changes are not parallel in many cases, MR imaging may have a role in monitoring masses in patients with lymphoma. Signal intensity patterns, however, reflect gross histologic characteristics and cannot be considered specific, especially in the first 6 months after initiation of therapy.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 445-451 |
| Number of pages | 7 |
| Journal | Radiology |
| Volume | 188 |
| Issue number | 2 |
| State | Published - Aug 1993 |
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Keywords
- Lymphoma, MR, 34.121411, 60.121411, 67.121411
- Lymphoma, therapy, 34.1299, 60.1299, 67.1299
ASJC Scopus subject areas
- Radiological and Ultrasound Technology
Cite this
Lymphoma : Monitoring tumor size and signal intensity with MR imaging. / Rahmouni, Alain; Tempany, Clare; Jones, Richard J; Mann, Risa; Yang, Andrew; Zerhouni, Elias.
In: Radiology, Vol. 188, No. 2, 08.1993, p. 445-451.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Lymphoma
T2 - Monitoring tumor size and signal intensity with MR imaging
AU - Rahmouni, Alain
AU - Tempany, Clare
AU - Jones, Richard J
AU - Mann, Risa
AU - Yang, Andrew
AU - Zerhouni, Elias
PY - 1993/8
Y1 - 1993/8
N2 - To assess the potential value of magnetic resonance (MR) imaging in monitoring disease status, 34 patients with residual masses underwent MR imaging at sequential intervals. Patterns of signal intensity suggestive of active and inactive residual disease were compared to changes in tumor size. The signal intensity pattern was suggestive of persistent disease in 18 patients, even though tumor size was stable or decreased. Three of these patterns, seen within 6 months of initiation of therapy, were due to necrosis or inflammation. The MR imaging assessment of inactive disease was confirmed in 15 of the remaining 16 patients. In no case was an increase in tumor size seen in conjunction with a decrease in signal intensity. Because tumor size and signal intensity changes are not parallel in many cases, MR imaging may have a role in monitoring masses in patients with lymphoma. Signal intensity patterns, however, reflect gross histologic characteristics and cannot be considered specific, especially in the first 6 months after initiation of therapy.
AB - To assess the potential value of magnetic resonance (MR) imaging in monitoring disease status, 34 patients with residual masses underwent MR imaging at sequential intervals. Patterns of signal intensity suggestive of active and inactive residual disease were compared to changes in tumor size. The signal intensity pattern was suggestive of persistent disease in 18 patients, even though tumor size was stable or decreased. Three of these patterns, seen within 6 months of initiation of therapy, were due to necrosis or inflammation. The MR imaging assessment of inactive disease was confirmed in 15 of the remaining 16 patients. In no case was an increase in tumor size seen in conjunction with a decrease in signal intensity. Because tumor size and signal intensity changes are not parallel in many cases, MR imaging may have a role in monitoring masses in patients with lymphoma. Signal intensity patterns, however, reflect gross histologic characteristics and cannot be considered specific, especially in the first 6 months after initiation of therapy.
KW - Lymphoma, MR, 34.121411, 60.121411, 67.121411
KW - Lymphoma, therapy, 34.1299, 60.1299, 67.1299
UR - http://www.scopus.com/inward/record.url?scp=0027234557&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0027234557&partnerID=8YFLogxK
M3 - Article
C2 - 8327695
AN - SCOPUS:0027234557
VL - 188
SP - 445
EP - 451
JO - Radiology
JF - Radiology
SN - 0033-8419
IS - 2
ER -