Lymphoepithelioma-like carcinoma of the urinary bladder: Report of a rare case

Naorem Gopendro Singh, A. A S R Mannan, Amre A. Rifaat, Mirza Kahvic

Research output: Contribution to journalArticle

Abstract

Lymphoepithelioma-like carcinoma (LELC) is a rare malignant neoplasm in the urinary bladder, which can histologically mimic lymphoma, poorly differentiated invasive transitional cell carcinoma or poorly differentiated squamous cell carcinoma with a lymphoplasmacytic background. A urinary bladder tumor was identified in a 65-year-old man suffering from hematuria for several weeks. Transurethral biopsy revealed an undifferentiated tumor with prominent lymphocytes and plasma cell infiltration. Immunohistochemical evaluation showed positive staining for cytokeratin and epithelial membrane antigen. Subsequent radical cystectomy showed pure LELC. We present the case to highlight the significance of recognizing this unusual bladder tumor and discuss the important differential diagnosis, treatment options and prognosis.

Original languageEnglish (US)
Pages (from-to)478-481
Number of pages4
JournalAnnals of Saudi Medicine
Volume29
Issue number6
DOIs
StatePublished - Nov 1 2009
Externally publishedYes

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Urinary Bladder Neoplasms
Urinary Bladder
Carcinoma
Mucin-1
Transitional Cell Carcinoma
Cystectomy
Hematuria
Keratins
Plasma Cells
Squamous Cell Carcinoma
Lymphoma
Differential Diagnosis
Lymphocytes
Staining and Labeling
Biopsy
Neoplasms
Therapeutics

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Lymphoepithelioma-like carcinoma of the urinary bladder : Report of a rare case. / Singh, Naorem Gopendro; Mannan, A. A S R; Rifaat, Amre A.; Kahvic, Mirza.

In: Annals of Saudi Medicine, Vol. 29, No. 6, 01.11.2009, p. 478-481.

Research output: Contribution to journalArticle

Singh, Naorem Gopendro ; Mannan, A. A S R ; Rifaat, Amre A. ; Kahvic, Mirza. / Lymphoepithelioma-like carcinoma of the urinary bladder : Report of a rare case. In: Annals of Saudi Medicine. 2009 ; Vol. 29, No. 6. pp. 478-481.
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