Lymphocyte transformation in patients with staged mycosis fungoides and Sezary syndrome

A. Du Vivier, R. A. Harper, E. Vonderheid, E. J. Van Scott

Research output: Contribution to journalArticle

Abstract

Lymphocyte transformation was studied in patients with mycosis fungoides and the Sezary syndrome with particular reference to the stage of disease. Phytohemagglutinin-induced lymphocyte blastogenesis was normal in stage II, became depressed in stage III and was greatly reduced in stage IV disease. Similar abnormalities were found in patients with the Sezary syndrome once the proportion of abnormal cells in the peripheral blood exceeded 10%. It is concluded that stage III mycosis fungoides is probably a critical period in determining dissemination of the disease.

Original languageEnglish (US)
Pages (from-to)209-213
Number of pages5
JournalCancer
Volume42
Issue number1
StatePublished - 1978
Externally publishedYes

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Sezary Syndrome
Mycosis Fungoides
Lymphocyte Activation
Phytohemagglutinins
Lymphocytes

ASJC Scopus subject areas

  • Cancer Research
  • Oncology

Cite this

Du Vivier, A., Harper, R. A., Vonderheid, E., & Van Scott, E. J. (1978). Lymphocyte transformation in patients with staged mycosis fungoides and Sezary syndrome. Cancer, 42(1), 209-213.

Lymphocyte transformation in patients with staged mycosis fungoides and Sezary syndrome. / Du Vivier, A.; Harper, R. A.; Vonderheid, E.; Van Scott, E. J.

In: Cancer, Vol. 42, No. 1, 1978, p. 209-213.

Research output: Contribution to journalArticle

Du Vivier, A, Harper, RA, Vonderheid, E & Van Scott, EJ 1978, 'Lymphocyte transformation in patients with staged mycosis fungoides and Sezary syndrome', Cancer, vol. 42, no. 1, pp. 209-213.
Du Vivier A, Harper RA, Vonderheid E, Van Scott EJ. Lymphocyte transformation in patients with staged mycosis fungoides and Sezary syndrome. Cancer. 1978;42(1):209-213.
Du Vivier, A. ; Harper, R. A. ; Vonderheid, E. ; Van Scott, E. J. / Lymphocyte transformation in patients with staged mycosis fungoides and Sezary syndrome. In: Cancer. 1978 ; Vol. 42, No. 1. pp. 209-213.
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