Lymphatic spread of pagetic osteogenic sarcoma detected by bone scan

Alexandre Arkader, Carol D Morris

Research output: Contribution to journalArticle

Abstract

Bone scans are widely utilized for detection of metastases from bone sarcomas. Technetium methylene diphosphonate scan ([99mTc]MDP) is one of the most popular radiotracers used for that purpose. Lymphatic spread of bone sarcomas is unusual and often difficult to diagnose. Unfortunately, bone scans are not as sensitive in demonstrating lymphatic spread of sarcomas as they are at demonstrating hematogenous spread. A bone scan win often fail to demonstrate lymph nodes metastases until there is mineralization at the affected node. In this report, we highlight an interesting case of a patient with secondary osteogenic sarcoma (OS) from Paget's disease in the distal femur with non-ossified inguinal nodal metastasis diagnosed with [99mTc]MDP. Lymph node involvement was not appreciated on plain radiographs or computed tomography (CT).

Original languageEnglish (US)
Pages (from-to)131-134
Number of pages4
JournalCancer Imaging
Volume8
Issue number1
DOIs
StatePublished - 2008
Externally publishedYes

Fingerprint

Osteosarcoma
Technetium Tc 99m Medronate
Bone and Bones
Neoplasm Metastasis
Sarcoma
Lymph Nodes
Groin
Femur
Non-Hodgkin's Lymphoma
Tomography

Keywords

  • Bone scan
  • Lymph node metastasis
  • Metastatic sarcoma
  • Paget's sarcoma

ASJC Scopus subject areas

  • Oncology
  • Radiology Nuclear Medicine and imaging
  • Radiological and Ultrasound Technology

Cite this

Lymphatic spread of pagetic osteogenic sarcoma detected by bone scan. / Arkader, Alexandre; Morris, Carol D.

In: Cancer Imaging, Vol. 8, No. 1, 2008, p. 131-134.

Research output: Contribution to journalArticle

@article{e7b76963914c419c996c9b92ef915c56,
title = "Lymphatic spread of pagetic osteogenic sarcoma detected by bone scan",
abstract = "Bone scans are widely utilized for detection of metastases from bone sarcomas. Technetium methylene diphosphonate scan ([99mTc]MDP) is one of the most popular radiotracers used for that purpose. Lymphatic spread of bone sarcomas is unusual and often difficult to diagnose. Unfortunately, bone scans are not as sensitive in demonstrating lymphatic spread of sarcomas as they are at demonstrating hematogenous spread. A bone scan win often fail to demonstrate lymph nodes metastases until there is mineralization at the affected node. In this report, we highlight an interesting case of a patient with secondary osteogenic sarcoma (OS) from Paget's disease in the distal femur with non-ossified inguinal nodal metastasis diagnosed with [99mTc]MDP. Lymph node involvement was not appreciated on plain radiographs or computed tomography (CT).",
keywords = "Bone scan, Lymph node metastasis, Metastatic sarcoma, Paget's sarcoma",
author = "Alexandre Arkader and Morris, {Carol D}",
year = "2008",
doi = "10.1102/1470-7330.2008.0021",
language = "English (US)",
volume = "8",
pages = "131--134",
journal = "Cancer Imaging",
issn = "1740-5025",
publisher = "e-med",
number = "1",

}

TY - JOUR

T1 - Lymphatic spread of pagetic osteogenic sarcoma detected by bone scan

AU - Arkader, Alexandre

AU - Morris, Carol D

PY - 2008

Y1 - 2008

N2 - Bone scans are widely utilized for detection of metastases from bone sarcomas. Technetium methylene diphosphonate scan ([99mTc]MDP) is one of the most popular radiotracers used for that purpose. Lymphatic spread of bone sarcomas is unusual and often difficult to diagnose. Unfortunately, bone scans are not as sensitive in demonstrating lymphatic spread of sarcomas as they are at demonstrating hematogenous spread. A bone scan win often fail to demonstrate lymph nodes metastases until there is mineralization at the affected node. In this report, we highlight an interesting case of a patient with secondary osteogenic sarcoma (OS) from Paget's disease in the distal femur with non-ossified inguinal nodal metastasis diagnosed with [99mTc]MDP. Lymph node involvement was not appreciated on plain radiographs or computed tomography (CT).

AB - Bone scans are widely utilized for detection of metastases from bone sarcomas. Technetium methylene diphosphonate scan ([99mTc]MDP) is one of the most popular radiotracers used for that purpose. Lymphatic spread of bone sarcomas is unusual and often difficult to diagnose. Unfortunately, bone scans are not as sensitive in demonstrating lymphatic spread of sarcomas as they are at demonstrating hematogenous spread. A bone scan win often fail to demonstrate lymph nodes metastases until there is mineralization at the affected node. In this report, we highlight an interesting case of a patient with secondary osteogenic sarcoma (OS) from Paget's disease in the distal femur with non-ossified inguinal nodal metastasis diagnosed with [99mTc]MDP. Lymph node involvement was not appreciated on plain radiographs or computed tomography (CT).

KW - Bone scan

KW - Lymph node metastasis

KW - Metastatic sarcoma

KW - Paget's sarcoma

UR - http://www.scopus.com/inward/record.url?scp=46649115154&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=46649115154&partnerID=8YFLogxK

U2 - 10.1102/1470-7330.2008.0021

DO - 10.1102/1470-7330.2008.0021

M3 - Article

VL - 8

SP - 131

EP - 134

JO - Cancer Imaging

JF - Cancer Imaging

SN - 1740-5025

IS - 1

ER -