Lymphatic and blood vessel density in human conjunctiva after glaucoma filtration surgery

Rachida A. Bouhenni, Ibrahim Al Jadaan, Heidi Rassavong, Sami Al Shahwan, Hind Al Katan, Jeffrey Dunmire, Mirela Krasniqi, Deepak P. Edward

Research output: Contribution to journalArticlepeer-review

Abstract

Purpose: To investigate the lymphatic vascular microvessel density (LVD) and the blood vascular microvessel density (MVD) and their distribution in excised leaking blebs after mitomycin C trabeculectomy and normal conjunctiva specimens. Materials and Methods: LVD and MVD in normal human conjunctiva (n=8) and excised blebs in the hypocellular stroma and peribleb tissue (conjunctiva adjacent to hypocellular bleb tissue) (n=8) were evaluated by immunohistochemistry using antibodies raised against Lymphatic Vessel Endothelial Receptor 1 (D2-40, lymphatic endothelium) and CD34 (vascular endothelium). LVD and MVD counts were performed by light microscopyin 5 fields at ×20 magnification by 3 observers. Differences were determined using Mann-Whitney U test (P

Original languageEnglish (US)
Pages (from-to)e35-e38
JournalJournal of Glaucoma
Volume25
Issue number1
DOIs
StatePublished - 2016

Keywords

  • Blebitis
  • Lymphatic vessels
  • Mitomycin c
  • Trabeculectomy

ASJC Scopus subject areas

  • Ophthalmology

Fingerprint Dive into the research topics of 'Lymphatic and blood vessel density in human conjunctiva after glaucoma filtration surgery'. Together they form a unique fingerprint.

Cite this