Lymphatic and blood vessel density in human conjunctiva after glaucoma filtration surgery

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Abstract

Purpose: To investigate the lymphatic vascular microvessel density (LVD) and the blood vascular microvessel density (MVD) and their distribution in excised leaking blebs after mitomycin C trabeculectomy and normal conjunctiva specimens. Materials and Methods: LVD and MVD in normal human conjunctiva (n=8) and excised blebs in the hypocellular stroma and peribleb tissue (conjunctiva adjacent to hypocellular bleb tissue) (n=8) were evaluated by immunohistochemistry using antibodies raised against Lymphatic Vessel Endothelial Receptor 1 (D2-40, lymphatic endothelium) and CD34 (vascular endothelium). LVD and MVD counts were performed by light microscopyin 5 fields at ×20 magnification by 3 observers. Differences were determined using Mann-Whitney U test (P

Original languageEnglish (US)
Pages (from-to)e35-e38
JournalJournal of Glaucoma
Volume25
Issue number1
DOIs
Publication statusPublished - 2016

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Keywords

  • Blebitis
  • Lymphatic vessels
  • Mitomycin c
  • Trabeculectomy

ASJC Scopus subject areas

  • Ophthalmology

Cite this

Bouhenni, R. A., Jadaan, I. A., Rassavong, H., Shahwan, S. A., Katan, H. A., Dunmire, J., ... Edward, D. P. (2016). Lymphatic and blood vessel density in human conjunctiva after glaucoma filtration surgery. Journal of Glaucoma, 25(1), e35-e38. https://doi.org/10.1097/IJG.0000000000000199