Lymph node counts are valid indicators of the quality of surgical care in bladder cancer: A population-based study

D. Robert Siemens, William J. Mackillop, Yingwei Peng, Xuejiao Wei, David Berman, Christopher M. Booth

Research output: Contribution to journalArticle

Abstract

Objective: To describe lymph node counts in routine clinical practice and evaluate their association with outcomes to explore its utility as a quality indicator. Methods and materials: Electronic records of treatment and surgical pathology reports were linked with the population-based Ontario Cancer Registry to identify all patients who underwent cystectomy between 1994 and 2008. Temporal trends were described over 3 periods: 1994 to 1998, 1999 to 2000, and 2004 to 2008. Multivariate generalized linear regression analysis was used to determine the factors associated with the use of pelvic lymph node dissection (PLND). A Cox proportional hazards regression model was used to explore the associations between PLND and survival. Results: The study population included 2,802 patients. Use of PLND (50%, 62%, and 85%, correspondingly), median node yield (5, 6, and 9, correspondingly), and node density (56%, 50%, and 39%, correspondingly) all improved over the study periods, 1994 to 1998, 1999 to 2000, and 2004 to 2008 (P

Original languageEnglish (US)
Pages (from-to)425.e15-425.e23
JournalUrologic Oncology: Seminars and Original Investigations
Volume33
Issue number10
DOIs
StatePublished - Oct 1 2015
Externally publishedYes

Keywords

  • Bladder cancer
  • Lymph node dissection
  • Population
  • Surgical quality

ASJC Scopus subject areas

  • Oncology
  • Urology

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