Abstract
The effect of lung volume on the mechanical interdependence between an obstructed sublobar region of lung and its surroundings tissues was investigated in intact and isolated pig lungs. Interdependence is arbitrarily defined as the effectiveness with which the linkage between the region and surrounding tissue mediates a tendency for inflation to become even whenever it is uneven. When the volume of the surrounding lung (Vl) was high relative to the volume of the obstructed region (Vr), or when they were relatively equal at higher inflation states, interdependence decreased. When Vr was high relative to Vl, interdependence increased. From a consideration of the changes in regional shape observed during even and uneven inflation states it is suggested, that regional distortion and its effects on regional elastic recoil are important determinants of pulmonary interdependence.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 395-401 |
| Number of pages | 7 |
| Journal | Journal of Applied Physiology |
| Volume | 38 |
| Issue number | 3 |
| State | Published - 1975 |
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ASJC Scopus subject areas
- Endocrinology
- Physiology
- Orthopedics and Sports Medicine
- Physical Therapy, Sports Therapy and Rehabilitation
Cite this
Lung volume and interdependence in the pig. / Sylvester, J. T.; Menkes, H. A.; Stitik, F.
In: Journal of Applied Physiology, Vol. 38, No. 3, 1975, p. 395-401.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Lung volume and interdependence in the pig
AU - Sylvester, J. T.
AU - Menkes, H. A.
AU - Stitik, F.
PY - 1975
Y1 - 1975
N2 - The effect of lung volume on the mechanical interdependence between an obstructed sublobar region of lung and its surroundings tissues was investigated in intact and isolated pig lungs. Interdependence is arbitrarily defined as the effectiveness with which the linkage between the region and surrounding tissue mediates a tendency for inflation to become even whenever it is uneven. When the volume of the surrounding lung (Vl) was high relative to the volume of the obstructed region (Vr), or when they were relatively equal at higher inflation states, interdependence decreased. When Vr was high relative to Vl, interdependence increased. From a consideration of the changes in regional shape observed during even and uneven inflation states it is suggested, that regional distortion and its effects on regional elastic recoil are important determinants of pulmonary interdependence.
AB - The effect of lung volume on the mechanical interdependence between an obstructed sublobar region of lung and its surroundings tissues was investigated in intact and isolated pig lungs. Interdependence is arbitrarily defined as the effectiveness with which the linkage between the region and surrounding tissue mediates a tendency for inflation to become even whenever it is uneven. When the volume of the surrounding lung (Vl) was high relative to the volume of the obstructed region (Vr), or when they were relatively equal at higher inflation states, interdependence decreased. When Vr was high relative to Vl, interdependence increased. From a consideration of the changes in regional shape observed during even and uneven inflation states it is suggested, that regional distortion and its effects on regional elastic recoil are important determinants of pulmonary interdependence.
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UR - http://www.scopus.com/inward/citedby.url?scp=0016751029&partnerID=8YFLogxK
M3 - Article
C2 - 1150551
AN - SCOPUS:0016751029
VL - 38
SP - 395
EP - 401
JO - Journal of Applied Physiology
JF - Journal of Applied Physiology
SN - 0161-7567
IS - 3
ER -