Lung scan in the diagnosis and management of patent foramen ovale (pulmonary embolism, paradoxical embolism)

A. Cahid Civelek, Elcin Ozalp, Bernard L. Gerber, James Weiss

Research output: Contribution to journalArticle

Abstract

This case illustrates the reopening of foramen ovale in a young patient with chronic pulmonary hypertension caused by bronchiectasis and chronic pulmonary fibrosis, which resulted in a prominent right-to-left shunt and severe hypoxia. Her clinically unsuspected right-to-left shunt was discovered during ventilation-perfusion scan, which was performed for the evaluation of pulmonary embolism. She had common variable immune deficiency, a primary immunodeficiency disease in which B-lymphocytes produce few or no antibodies. Most patients with this syndrome have an intrinsic defect in their B-lymphocytes that results in reduced immunoglobulin production. In these patients, recurrent respiratory tract infections are common and may result in chronic lung disease, fibrosis, particularly bronchiectasis (20-30%) and even cor pulmonale as happened in our patient [1] [J. Clin. Immunol. 9 (1989) 22-33.].

Original languageEnglish (US)
Pages (from-to)349-352
Number of pages4
JournalClinical Imaging
Volume26
Issue number5
DOIs
StatePublished - Sep 1 2002

Keywords

  • Paradoxical embolism
  • Patent foramen ovale
  • Pulmonary embolism
  • V/Q scan

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

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