Low serum carotenoids are associated with a decline in walking speed in older women

N. Alipanah, R. Varadhan, Kai Sun, L. Ferrucci, L. P. Fried, Richard D. Semba

Research output: Contribution to journalArticlepeer-review

Abstract

Background and Objectives: Walking speed is an important measure of physical performance that is predictive of disability and mortality. The relationship of dietary factors to changes in physical performance has not been well characterized in older adults. The aim was to determine whether total serum carotenoid concentrations, a marker for fruit and vegetable intake, and serum selenium are related to changes in walking speed in older women. Subjects and Methods: The relationship between total serum carotenoids and selenium measured at baseline, 12, and 24 months follow-up and walking speed assessed at baseline and every six months for 36 months was examined in 687 moderately to severely disabled women, 65 years or older, living in the community. Results: Mean total serum carotenoids were associated with mean walking speed over three years of follow-up (P = 0.0003) and rate of change of walking speed (P = 0.007) in multivariate linear regression models adjusting for age, body mass index, and chronic diseases. Mean serum selenium was associated with mean walking speed over three years of follow-up (P = 0.0003) but not with the rate of change of walking speed (P = 0.26). Conclusions: These findings suggest that a higher fruit and vegetable intake, as indicated by higher total serum carotenoid concentrations, may be protective against a decline in walking speed in older women.

Original languageEnglish (US)
Pages (from-to)170-175
Number of pages6
JournalJournal of Nutrition, Health and Aging
Volume13
Issue number3
DOIs
StatePublished - Mar 2009

Keywords

  • Aging
  • Carotenoids
  • Disability
  • Walking speed
  • Women

ASJC Scopus subject areas

  • Medicine (miscellaneous)
  • Nutrition and Dietetics
  • Geriatrics and Gerontology

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