TY - JOUR
T1 - Low dietary fiber and high protein intakes associated with newly diagnosed diabetes in a remote aboriginal community
AU - Wolever, Thomas M.S.
AU - Hamad, Safa
AU - Gittelsohn, Joel
AU - Gao, Joe
AU - Hanley, Anthony J.G.
AU - Harris, Stewart B.
AU - Zinman, Bernard
N1 - Copyright:
Copyright 2018 Elsevier B.V., All rights reserved.
PY - 1997
Y1 - 1997
N2 - The high prevalence of diabetes mellitus in North American aboriginal populations may be due to recent changes in lifestyle, including the adoption of a high-fat, low-fiber diet. To determine whether fat or fiber intakes were associated with new cases of diabetes, we studied 72% (728/1018) of residents aged > 9 y from a remote aboriginal community in northern Ontario using the 75-g oral-glucose-tolerance test and 24-h dietary recall. The mean fat intake of this population (36% of energy) was typical for North America, but faber intake (1.2 g/MJ) was very low. Logistic-regression analysis, adjusted for age, sex, and body mass index, showed that a 1-SD increase in faber intake reduced the risk of having diabetes by 39% (P = 0.026) whereas the same increase in protein intake increased the risk by 38% (P = 0.027). There was no significant effect of energy, fat, starch, or simple sugars. These data support Trowell's original dietary-fiber hypothesis that '... dietary fiber depleted starchy foods are conducive to the development of diabetes mellitus in susceptible human genotypes'.
AB - The high prevalence of diabetes mellitus in North American aboriginal populations may be due to recent changes in lifestyle, including the adoption of a high-fat, low-fiber diet. To determine whether fat or fiber intakes were associated with new cases of diabetes, we studied 72% (728/1018) of residents aged > 9 y from a remote aboriginal community in northern Ontario using the 75-g oral-glucose-tolerance test and 24-h dietary recall. The mean fat intake of this population (36% of energy) was typical for North America, but faber intake (1.2 g/MJ) was very low. Logistic-regression analysis, adjusted for age, sex, and body mass index, showed that a 1-SD increase in faber intake reduced the risk of having diabetes by 39% (P = 0.026) whereas the same increase in protein intake increased the risk by 38% (P = 0.027). There was no significant effect of energy, fat, starch, or simple sugars. These data support Trowell's original dietary-fiber hypothesis that '... dietary fiber depleted starchy foods are conducive to the development of diabetes mellitus in susceptible human genotypes'.
KW - Amerindians
KW - Diabetes mellitus
KW - Dietary fiber
KW - Ontario
KW - Protein
KW - Sandy Lake Health and Diabetes Project
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U2 - 10.1093/ajcn/66.6.1470
DO - 10.1093/ajcn/66.6.1470
M3 - Article
C2 - 9394701
AN - SCOPUS:0030833906
VL - 66
SP - 1470
EP - 1474
JO - American Journal of Clinical Nutrition
JF - American Journal of Clinical Nutrition
SN - 0002-9165
IS - 6
ER -