Low- and high-tech approaches to control plasmodium parasite transmission by anopheles mosquitoes

George Dimopoulos, Chris M. Cirimotich, April M. Clayton

Research output: Contribution to journalReview article

Abstract

Current efforts have proven inadequate to stop the transmission of Plasmodium parasites, and hence the spread of malaria, by Anopheles mosquitoes. Therefore, a novel arsenal of strategies for inhibiting Plasmodium infection of mosquitoes is urgently needed. In this paper, we summarize research on two approaches to malaria control, a low-tech strategy based on parasite inhibition by the mosquito's natural microflora, and a high-tech strategy using genetic modification of mosquitoes that renders them resistant to infection and discuss advantages and disadvantages for both approaches.

Original languageEnglish (US)
Article number891342
JournalJournal of Tropical Medicine
DOIs
StatePublished - 2011

ASJC Scopus subject areas

  • Parasitology
  • Microbiology

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