Loss-of-function mutations in the RNA biogenesis factor NAF1 predispose to pulmonary fibrosis-emphysema

Medicine & Life Sciences

• telomerase RNA 100%
• Pulmonary Emphysema 89%
• Pulmonary Fibrosis 78%
• Loss of Function Mutation 77%
• Frameshift Mutation 55%
• Clustered Regularly Interspaced Short Palindromic Repeats 52%
• Telomere 50%
• RNA 47%
• NFI Transcription Factors 33%
• Telomere Homeostasis 33%
• Small Nucleolar RNA 32%
• Premature Aging 30%
• Haploinsufficiency 29%
• Myelodysplastic Syndromes 25%
• Mutation 25%
• Chronic Obstructive Pulmonary Disease 20%
• Liver Diseases 19%
• Pathology 14%
• Phenotype 13%
• Genes 9%
• Proteins 8%