Longitudinal study of quality of life in people with advanced Alzheimer's disease

Steven M. Albert; Diane M. Jacobs; Mary Sano; Karen Marder; Karen Bell; Davangere Devanand; Jason Brandt; Marilyn Albert; Yaakov Stern

doi:10.1097/00019442-200105000-00008

Longitudinal study of quality of life in people with advanced Alzheimer's disease

Steven M. Albert, Diane M. Jacobs, Mary Sano, Karen Marder, Karen Bell, Davangere Devanand, Jason Brandt, Marilyn Albert, Yaakov Stern

Research output: Contribution to journal › Article › peer-review

Abstract

The authors examined three indicators of health-related quality of life in people with advanced Alzheimer's disease ([AD]; N = 150): confinement to home, null activity, and null positive affect, as reported by patient proxies. Dementia severity predicted time-to-onset for all three disease milestones in models that controlled for sociodemographic indicators, nursing home status, and death in the follow-up period. Patients whose dementia worsened over follow-up were more likely to reach each milestone. These outcomes represent key milestones in the care of patients; they are sensitive to disease progression, and they are likely to be useful for studying treatment in advanced AD.

Original language	English (US)
Pages (from-to)	160-168
Number of pages	9
Journal	American Journal of Geriatric Psychiatry
Volume	9
Issue number	2
DOIs	https://doi.org/10.1097/00019442-200105000-00008
State	Published - Jan 1 2001
Externally published	Yes

ASJC Scopus subject areas

Geriatrics and Gerontology
Psychiatry and Mental health

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Longitudinal study of quality of life in people with advanced Alzheimer's disease. / Albert, Steven M.; Jacobs, Diane M.; Sano, Mary; Marder, Karen; Bell, Karen; Devanand, Davangere; Brandt, Jason ; Albert, Marilyn; Stern, Yaakov.

In: American Journal of Geriatric Psychiatry, Vol. 9, No. 2, 01.01.2001, p. 160-168.

Research output: Contribution to journal › Article › peer-review

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