Abstract
This paper proposes an extension of generalized linear models to the analysis of longitudinal data. We introduce a class of estimating equations that give consistent estimates of the regression parameters and of their variance under mild assumptions about the time dependence. The estimating equations are derived without specifying the joint distribution of a subject's observations yet they reduce to the score equations for niultivariate Gaussian outcomes. Asymptotic theory is presented for the general class of estimators. Specific cases in which we assume independence, m-dependence and exchangeable correlation structures from each subject are discussed. Efficiency of the pioposecl estimators in two simple situations is considered. The approach is closely related to quasi-likelihood.
Original language | English (US) |
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Pages (from-to) | 13-22 |
Number of pages | 10 |
Journal | Biometrika |
Volume | 73 |
Issue number | 1 |
DOIs | |
State | Published - Apr 1986 |
Keywords
- Estimating equation
- Generalized linear model
- Longitudinal data
- Quasi-likelihood
- Repeated measures
ASJC Scopus subject areas
- Statistics and Probability
- General Mathematics
- Agricultural and Biological Sciences (miscellaneous)
- General Agricultural and Biological Sciences
- Statistics, Probability and Uncertainty
- Applied Mathematics