Long term therapy of hereditary angioedema (HAE). Preventive management with fluoxymesterone and oxymetholone in severely affected males and females

P. J. Davis, F. B. Davis, P. Charache

Research output: Contribution to journalArticle

Abstract

Eleven patients with hereditary angioedema (HAE) received long term androgen therapy in a preventive management protocol. Experience of 317 patient months in severely affected males who received fluoxymesterone and 116 patient months in females who received oxymetholone showed a significant reduction in attack rate or severity of attacks of oropharyngeal and peripheral edema and abdominal pain, compared with pretreatment attack rate or attack rate during lapses in therapy. No episodes of laryngeal edema occurred in patients on androgen therapy.

Original languageEnglish (US)
Pages (from-to)391-398
Number of pages8
JournalJohns Hopkins Medical Journal
Volume135
Issue number6
StatePublished - Dec 1 1974

ASJC Scopus subject areas

  • Medicine(all)

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