Long-term safety and efficacy of a cholesterol-lowering diet in children with elevated low-density lipoprotein cholesterol: Seven-year results of the dietary intervention study in children (DISC)

Eva Obarzanek, Sue Y S Kimm, Bruce A. Barton, Linda Van Horn, Peter O. Kwiterovich, Denise G. Simons-Morton, Sally A. Hunsberger, Norman L. Lasser, Alan M. Robson, Frank A. Franklin, Ronald M. Lauer, Victor J. Stevens, Lisa Aronson Friedman, Joanne F. Dorgan, Merwyn R. Greenlick

Research output: Contribution to journalArticle

Abstract

Objective. Diets reduced in fat and cholesterol are recommended for children over 2 years of age, yet long-term safety and efficacy are unknown. This study tests the long-term efficacy and safety of a cholesterol-lowering dietary intervention in children. Methods. Six hundred sixty-three children 8 to 10 years of age with elevated low-density lipoprotein cholesterol (LDL-C) were randomized to a dietary intervention or usual care group, with a mean of 7.4 years' follow-up. The dietary behavioral intervention promoted adherence to a diet with 28% of energy from total fat,

Original languageEnglish (US)
Pages (from-to)256-264
Number of pages9
JournalPediatrics
Volume107
Issue number2
DOIs
StatePublished - 2001

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LDL Cholesterol
Cholesterol
Diet
Safety
Fats
Dietary Cholesterol

Keywords

  • Children
  • Fat intake
  • Saturated fat
  • Serum cholesterol

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health

Cite this

Long-term safety and efficacy of a cholesterol-lowering diet in children with elevated low-density lipoprotein cholesterol : Seven-year results of the dietary intervention study in children (DISC). / Obarzanek, Eva; Kimm, Sue Y S; Barton, Bruce A.; Van Horn, Linda; Kwiterovich, Peter O.; Simons-Morton, Denise G.; Hunsberger, Sally A.; Lasser, Norman L.; Robson, Alan M.; Franklin, Frank A.; Lauer, Ronald M.; Stevens, Victor J.; Friedman, Lisa Aronson; Dorgan, Joanne F.; Greenlick, Merwyn R.

In: Pediatrics, Vol. 107, No. 2, 2001, p. 256-264.

Research output: Contribution to journalArticle

Obarzanek, E, Kimm, SYS, Barton, BA, Van Horn, L, Kwiterovich, PO, Simons-Morton, DG, Hunsberger, SA, Lasser, NL, Robson, AM, Franklin, FA, Lauer, RM, Stevens, VJ, Friedman, LA, Dorgan, JF & Greenlick, MR 2001, 'Long-term safety and efficacy of a cholesterol-lowering diet in children with elevated low-density lipoprotein cholesterol: Seven-year results of the dietary intervention study in children (DISC)', Pediatrics, vol. 107, no. 2, pp. 256-264. https://doi.org/10.1542/peds.107.2.256
Obarzanek, Eva ; Kimm, Sue Y S ; Barton, Bruce A. ; Van Horn, Linda ; Kwiterovich, Peter O. ; Simons-Morton, Denise G. ; Hunsberger, Sally A. ; Lasser, Norman L. ; Robson, Alan M. ; Franklin, Frank A. ; Lauer, Ronald M. ; Stevens, Victor J. ; Friedman, Lisa Aronson ; Dorgan, Joanne F. ; Greenlick, Merwyn R. / Long-term safety and efficacy of a cholesterol-lowering diet in children with elevated low-density lipoprotein cholesterol : Seven-year results of the dietary intervention study in children (DISC). In: Pediatrics. 2001 ; Vol. 107, No. 2. pp. 256-264.
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AU - Kimm, Sue Y S

AU - Barton, Bruce A.

AU - Van Horn, Linda

AU - Kwiterovich, Peter O.

AU - Simons-Morton, Denise G.

AU - Hunsberger, Sally A.

AU - Lasser, Norman L.

AU - Robson, Alan M.

AU - Franklin, Frank A.

AU - Lauer, Ronald M.

AU - Stevens, Victor J.

AU - Friedman, Lisa Aronson

AU - Dorgan, Joanne F.

AU - Greenlick, Merwyn R.

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