Long-term neuropsychological follow-up of a child with Klüver-Bucy syndrome

Morris J. Cohen, Yong D. Park, Hyunmi Kim, Jay J. Pillai

Research output: Contribution to journalArticle

Abstract

We describe the case of a 10-year-old girl who developed behavioral changes consistent with Klüver-Bucy Syndrome following Listeria meningoencephalitis at 21/2 years of age. MRI at age 4 revealed evidence of diffuse brain atrophy with predominant temporal lobe involvement. Electroencephalograpy at 91/2 years of age showed abnormal electrical discharges from the left temporal area. Follow-up MRI with volumetric analysis of the mesial temporal structures at 9 years of age demonstrated decreased hippocampal volume bilaterally. Consistent with the morphological abnormalities, serial neuropsychological evaluations demonstrated expressive and receptive language impairment and an amnestic syndrome that significantly decreased her ability to make new declarative memories and maintain adequate academic progress.

Original languageEnglish (US)
Pages (from-to)643-646
Number of pages4
JournalEpilepsy and Behavior
Volume19
Issue number4
DOIs
StatePublished - Dec 1 2010
Externally publishedYes

Keywords

  • Child
  • Kluver-Bucy syndrome
  • Neuropsychological follow-up

ASJC Scopus subject areas

  • Neurology
  • Clinical Neurology
  • Behavioral Neuroscience

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