Long-term efficacy, safety and tolerability of Remoxy for the management of chronic pain

Joseph V. Pergolizzi, Gianpietro Zampogna, Robert Taylor, Robert B. Raffa

Research output: Contribution to journalArticlepeer-review

Abstract

Historically, chronic pain generally went under-treated for a variety of objective and subjective reasons, including difficulty to objectively diagnose and manage over a long period of time, potential serious adverse effects of commonly available medications, and patient, healthcare and societal concerns over opioid medications. More recently, in an effort to redress the under-treatment of pain, the number of prescriptions of opioid analgesics has risen dramatically. However, paralleling the increased legitimate use has been a concomitant increase in opioid abuse, misuse and diversion. Pharmaceutical companies have responded by developing a variety of opioid formulations designed to deter abuse by making the products more difficult to tamper with. One such product is Remoxy®, an extended-release formulation of the strong opioid oxycodone. We review the efficacy, safety and tolerability of this formulation based on the available published literature.

Original languageEnglish (US)
Pages (from-to)231-238
Number of pages8
JournalExpert Review of Neurotherapeutics
Volume15
Issue number3
DOIs
StatePublished - Mar 1 2015

Keywords

  • abuse
  • abuse-deterrent
  • chronic pain
  • opioid
  • oxycodone
  • Remoxy

ASJC Scopus subject areas

  • Clinical Neurology
  • Neuroscience(all)
  • Pharmacology (medical)
  • Medicine(all)

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