Long-term effects of prenatal x-ray of human females

III. Mortality and morbidity

Mary B. Meyer, James A Tonascia

Research output: Contribution to journalArticle

Abstract

Experimental studies and long-term studies of humans exposed to ionizing radiation in utero and after birth show that these exposures increase the risk of cancer in childhood and in later life. A possible life-shortening effect has also been reported. This study followed to their mid-twenties 1458 women exposed in utero to diagnostic x-rays and 1458 matched, unexposed controls in Baltimore, Maryland, and obtained responses from over 1100 women in each group. Information about general health and specific diseases was obtained from questionnaires. Deaths were ascertained through famliy members and death certificates. Mortality rates were slightly higher among exposed than control women, and did not differ by gestational age at the time of exposure. Exposed women reported poor general health significantly more often than controls. Specific diseases occurred similarly in the two groups, although exposed women reported more epilepsy or fits, more ovarian tumors, and more high blood pressure. The strong correlation between weight and high blood pressure and the heavier weights of exposed women seemed to account for this difference. In summary, these matched exposed and control women, followed to their mid-twenties, experienced similar rates of morbidity and mortality. Radiation-induced cancers and life-shortening effects, if any, might not become evident until older ages.

Original languageEnglish (US)
Pages (from-to)327-336
Number of pages10
JournalAmerican Journal of Epidemiology
Volume114
Issue number3
StatePublished - Sep 1981

Fingerprint

X-Rays
Morbidity
Mortality
Radiation-Induced Neoplasms
Hypertension
Weights and Measures
Baltimore
Death Certificates
Health
Ionizing Radiation
Gestational Age
Epilepsy
Neoplasms
Parturition

Keywords

  • Health status
  • Morbidity
  • Mortality
  • Pelvimetry
  • Radiation effects
  • X-ray, diagnostic

ASJC Scopus subject areas

  • Geriatrics and Gerontology
  • Epidemiology

Cite this

Long-term effects of prenatal x-ray of human females : III. Mortality and morbidity. / Meyer, Mary B.; Tonascia, James A.

In: American Journal of Epidemiology, Vol. 114, No. 3, 09.1981, p. 327-336.

Research output: Contribution to journalArticle

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