Long-term effects of betamethasone on fetal development

J. W C Johnson, Wayne A Mitzner, J. C. Beck, W. T. London, D. L. Sly, P. A. Lee, V. A. Khouzami, R. L. Cavalieri

Research output: Contribution to journalArticle

Abstract

In previous studies, we noted that treatment of pregnant rhesus monkeys with betamethasone resulted in a marked increase in fetal lung distensibility. The purpose of the present study was to determine whether these changes persisted during subsequent in utero development. Pregnant rhesus monkeys were treated with 2 mg of betamethasone intramuscularly from day 120 to day 133 and underwent delivery by cesarean section one month later. The treated fetuses were found to have smaller lungs (-31%; p

Original languageEnglish (US)
Pages (from-to)1053-1064
Number of pages12
JournalAmerican Journal of Obstetrics and Gynecology
Volume141
Issue number8
StatePublished - 1981

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Betamethasone
Fetal Development
Macaca mulatta
Lung
Cesarean Section
Fetus

ASJC Scopus subject areas

  • Medicine(all)
  • Obstetrics and Gynecology

Cite this

Johnson, J. W. C., Mitzner, W. A., Beck, J. C., London, W. T., Sly, D. L., Lee, P. A., ... Cavalieri, R. L. (1981). Long-term effects of betamethasone on fetal development. American Journal of Obstetrics and Gynecology, 141(8), 1053-1064.

Long-term effects of betamethasone on fetal development. / Johnson, J. W C; Mitzner, Wayne A; Beck, J. C.; London, W. T.; Sly, D. L.; Lee, P. A.; Khouzami, V. A.; Cavalieri, R. L.

In: American Journal of Obstetrics and Gynecology, Vol. 141, No. 8, 1981, p. 1053-1064.

Research output: Contribution to journalArticle

Johnson, JWC, Mitzner, WA, Beck, JC, London, WT, Sly, DL, Lee, PA, Khouzami, VA & Cavalieri, RL 1981, 'Long-term effects of betamethasone on fetal development', American Journal of Obstetrics and Gynecology, vol. 141, no. 8, pp. 1053-1064.
Johnson JWC, Mitzner WA, Beck JC, London WT, Sly DL, Lee PA et al. Long-term effects of betamethasone on fetal development. American Journal of Obstetrics and Gynecology. 1981;141(8):1053-1064.
Johnson, J. W C ; Mitzner, Wayne A ; Beck, J. C. ; London, W. T. ; Sly, D. L. ; Lee, P. A. ; Khouzami, V. A. ; Cavalieri, R. L. / Long-term effects of betamethasone on fetal development. In: American Journal of Obstetrics and Gynecology. 1981 ; Vol. 141, No. 8. pp. 1053-1064.
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