Localizing arithmetic processes in the brain: Evidence from a transient deficit during cortical stimulation

John Whalen, Michael McCloskey, Ronald P. Lesser, Barry Gordon

Research output: Contribution to journalArticle


Although substantial progress has been made in characterizing the cognitive processes involved in simple arithmetic, the localization of these processes in the brain is not yet well understood. In this article we consider the localization of a specific arithmetic process, the retrieval of arithmetic table facts from memory. We report a single-patient study in which cortical stimulation was used to create transient disruption of brain activity in localized regions of the cortex. We show that stimulation at a left parietal site impaired performance on simple multiplication problems and further that the impairment reflected stimulation-induced disruption of arithmetic fact retrieval. Our findings support the hypothesis that the left parietal lobe is implicated in the arithmetic fact retrieval process.

Original languageEnglish (US)
Pages (from-to)409-417
Number of pages9
JournalJournal of cognitive neuroscience
Issue number3
StatePublished - Jan 1 1997


ASJC Scopus subject areas

  • Cognitive Neuroscience

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