Localized prostate cancer

Research output: Contribution to journalArticlepeer-review


A 68-year-old man presents with newly diagnosed prostate cancer. Over the past 3 years, his prostate-specific antigen level has slowly and steadily increased. His digital rectal examination is normal, the estimated prostate volume is 48 ml, and a needle-biopsy specimen reveals an adenocarcinoma with a Gleason score of 6 involving 10% of 1 of the 12 cores. He otherwise is well. How should his case be managed?

Original languageEnglish (US)
Pages (from-to)2696-2705
Number of pages10
JournalNew England Journal of Medicine
Issue number26
StatePublished - Dec 27 2007

ASJC Scopus subject areas

  • Medicine(all)

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