Localized benign pleural mesothelioma arising in a radiation field

Julie K. Hill, Richard F. Heitmiller, Frederic B. Askin, Janet E. Kuhlman

Research output: Contribution to journalArticlepeer-review


Localized benign pleural mesothelioma is a rare neoplasm representing less than 5% of all pleural tumors. Unlike the malignant diffuse pleural mesothelioma, there is no evidence of a relationship to asbestos exposure. Essentially, the cause of localized benign pleural mesotheliomas remains obscure. We propose that one mechanism of the development of this tumor is prior ionizing radiation to the tumor field. Ionizing radiation is a well-known human oncogen and leads to an increased incidence of benign tumors as well. A 65-year-old woman had a localized benign pleural mesothelioma of her left upper chest 22 years following adjuvant radiation therapy to the left breast and axillary region for a breast carcinoma.

Original languageEnglish (US)
Pages (from-to)189-194
Number of pages6
JournalClinical Imaging
Issue number3
StatePublished - May 1997


  • CT
  • Fibroma, benign pleural
  • Mesothelioma, benign pleural

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging


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