Localization of Transcranial Targets for Photoacoustic-Guided Endonasal Surgeries

Muyinatu A. Lediju Bell, Anastasia K. Ostrowski, Ke Li, Peter Kazanzides, Emad Boctor

Research output: Contribution to journalArticle

Abstract

Neurosurgeries to remove pituitary tumors using the endonasal, transsphenoidal approach often incur the risk of patient death caused by injury to the carotid arteries hidden by surrounding sphenoid bone. To avoid this risk, we propose intraoperative photoacoustic vessel visualization with an optical fiber attached to the surgical tool and an external ultrasound transducer placed on the temple. Vessel detection accuracy is limited by acoustic propagation properties, which were investigated with k-Wave simulations. In a two-layer model of temporal bone (3200. m/s sound speed, 1-4. mm thickness) and surrounding tissues, the localization error was ≤2. mm in the tranducer's axial dimension, while temporal bone curvature further degraded target localization. Phantom experiments revealed that multiple image targets (e.g. sphenoid bone and vessels) can be visualized, particularly with coherence-based beamforming, to determine tool-to-vessel proximity despite expected localization errors. In addition, the potential flexibility of the fiber position relative to the transducer and vessel was elucidated.

Original languageEnglish (US)
Pages (from-to)78-87
Number of pages10
JournalPhotoacoustics
Volume3
Issue number2
DOIs
StatePublished - Jun 1 2015

Fingerprint

Sphenoid Bone
Temporal Bone
Transducers
surgery
vessels
bones
Carotid Artery Injuries
Optical Fibers
Neurosurgery
Pituitary Neoplasms
Acoustics
transducers
acoustic propagation
beamforming
arteries
death
proximity
flexibility
tumors
optical fibers

Keywords

  • Coherence-based beamforming
  • Image-guided intervention
  • Transcranial imaging

ASJC Scopus subject areas

  • Atomic and Molecular Physics, and Optics
  • Radiology Nuclear Medicine and imaging

Cite this

Localization of Transcranial Targets for Photoacoustic-Guided Endonasal Surgeries. / Lediju Bell, Muyinatu A.; Ostrowski, Anastasia K.; Li, Ke; Kazanzides, Peter; Boctor, Emad.

In: Photoacoustics, Vol. 3, No. 2, 01.06.2015, p. 78-87.

Research output: Contribution to journalArticle

Lediju Bell, Muyinatu A. ; Ostrowski, Anastasia K. ; Li, Ke ; Kazanzides, Peter ; Boctor, Emad. / Localization of Transcranial Targets for Photoacoustic-Guided Endonasal Surgeries. In: Photoacoustics. 2015 ; Vol. 3, No. 2. pp. 78-87.
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