@article{3fdd3278133542a4b019eb2730965fb5,
title = "Localization of a murine oncornavirus 15,000-dalton virion protein on the membrane of neoplastic cells: Analysis by immunofluorescence and immunoelectron microscopy",
abstract = "A protein analogous to a 15,000-dalton structural protein of Rauscher murine oncornavirus has been localized on cell membranes of Rauscher erythroblastosis and CC57BR murine lymphosarcoma cells by use of monospecific antiserum in conjunction with immunofluorescence and immunoelectron microscopy techniques. Antigenic determinants of this protein were present on the membranes of erythroblastosis and lymphosarcoma cells, but were absent from the membrane of budding or mature virions. Both typespecific and group-specific determinants of the protein were accessible to antibodies reacting at the cell surface. This viral protein, expressed on the cell membrane, appears to correspond to previously described cell surface antigens of virus-induced murine leukemias.",
author = "Lejneva, {O. M.} and Abelev, {G. I.} and Dorfman, {N. A.} and M. Strand and August, {J. T.}",
note = "Funding Information: This work was carried out under the auspices of the U.S.S.R.-U.S.A. Health Agreement, Cancer Virology Group. It was supported in part by a Public Health Service Contract No. CP 33311-03 within the Virus Cancer Program of the National Cancer Institute, and by Grant No. GM 11301-13 from the National Institute of General Medical Sciences. REFERENCES AOKI, T., BOYSE, E. A., OLD, L. J., DE HARVEN, E., HAMMERLING, U., and WOOD, H. A. (1970). G. (Gross) and H-2 cell-surface antigens: Location on Gross leukemia cells by electron microscopy with visually labeled antibody. Proc. Nat. Acad. Sci. USA 65, 569-576. AUGUST, J. T., BOLOGNESI, D. P., FLEISSNER, E., GILDEN, R. V., and NOWINSKI, R. C. (1974). A proposed nomenclature for the virion proteins of oncogenic RNA viruses. Virology 60, 595-601. AVRAMEAS, S., and TERNYNCK, T. (1969). The cross-linking of protein with glutaraldehyde and its use for the preparation of immunoadsorbents. Zmmu-nochemistry 6, 53-66. BOYSE, E. A. (1973). Immuno-genetics in the study of cell surfaces: Some implications for morphogene-sis and cancer. In “Current Research in Oncology” (C. B. Anfinsen, M. Potter, and A. N. Schechter, eds.), pp. 57-94. Academic Press, New York and London. DEL VILLANO, B. C., NAVE, B., CROKER, B. P., LER-NER, R. A., and DIXON, F. J. (1975). The oncorna-virus glycoprotein gp69/71: A constituent of the surface of normal and malignant thymocytes. J. Exp. Med. 141, 172-187. DORFMAN, N. A. (1970). A method of preparing a monolayer of cells without tissue culture tech-nique. Proc. VII Znt. Congr. Electron Microscopy, Grenoble, 5633564. DORFMAN, N. A. (1971). The treatment of living cells with ferritin antibodies. Bull. Exp. Biol. Med. 12, 98-101. ENGELHARDT, N. V., ABELEV, G. I., and IEVLEVA, E. S. (1969). Group-and type-specific antigens of viral Rauscher leukemia. Voprosi Oncologii 10, 76-84. Copyright: Copyright 2014 Elsevier B.V., All rights reserved.",
year = "1976",
month = dec,
doi = "10.1016/0042-6822(76)90028-3",
language = "English (US)",
volume = "75",
pages = "281--292",
journal = "Virology",
issn = "0042-6822",
publisher = "Academic Press Inc.",
number = "2",
}