Local therapies of brain tumors with Gliadel® and GliaSite®: The North American experience

A. Olivi, J. Weingart

Research output: Contribution to journalArticlepeer-review

Abstract

Malignant brain tumors frequently recur at the site of the initial presentation. In recent years a number of innovative local treatments have been developed to achieve a more effective growth control. Among these, the Giadel® interstitial chemotherapy wafers and the GliaSite® Radiation Therapy System (RTS) have been the most extensively used in clinical settings with patients affected by malignant brain tumors. We present our experience with the use of these systems accumulated over the years. Both systems are now routinely employed in selected patients affected by Central Nervous System (CNS) malignancies. We provide a summary of the development, the initial applications, and the clinical lessons learned with their use. In addition we describe some of the future applications generated by these novel therapeutic concepts.

Original languageEnglish (US)
Pages (from-to)105-110
Number of pages6
JournalRivista Medica
Volume13
Issue number4
StatePublished - Dec 1 2007

Keywords

  • Brachytherapy
  • Glioblastoma multiforme
  • Interstitial chemotherapy
  • Malignant glioma

ASJC Scopus subject areas

  • Surgery
  • Psychiatry and Mental health

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