Local drug delivery

Raymond I. Haroun, Henry Brem

Research output: Contribution to journalReview article

Abstract

Intensive research efforts are now focused on the development of new strategies for more effective derivery of drugs to the central nervous system. These strategies include chemical modification of drugs, disruption of the blood-brain barrier, and utilization of alternative routes for drug delivery. This paper focuses on local drug delivery for the treatment of brain tumors. It reviews papers published in the past year on local chemotherapy and immunotherapy. Other aspects of local drug delivery are discussed, including convection-enhanced delivery and drug delivery via a controlled-release microchip.

Original languageEnglish (US)
Pages (from-to)187-193
Number of pages7
JournalCurrent opinion in oncology
Volume12
Issue number3
DOIs
StatePublished - Dec 1 2000

ASJC Scopus subject areas

  • Oncology
  • Cancer Research

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