Local control and reduced complications in split course irradiation of prostatic cancer

Jose L. Pino y Torres, Ding Jen Lee, Steven A. Leibel, Moody D. Wharam, Brett B. Cantrell, Dean S. Bross, Stanley E. Order

Research output: Contribution to journalArticlepeer-review

Abstract

Split course prostatic irradiation is a treatment technique where 4000-4500 rod whole pelvis irradiation is followed by two weeks of rest and an additional 2000-2500 rod by reduced field technique to a total dose of 6000-6500 rod. Eighty-four patients were studied and the results indicated a local regional control rate of 97.6% with an overall 3 year survival without evidence of disease of 96.6% for Stages A and B and 60% for Stage c. Significant complications occurred in 1.2 % of the patients. None of the patients needed surgical correction of a complication other than a perineal abscess. The risk/benefit ratio for pelvic and prostatic irradiation favors split course prostatic irradiation in that it demonstrates a low complication rate, high local regional control, and comparable disease-free survival to continuous irradiation.

Original languageEnglish (US)
Pages (from-to)43-47
Number of pages5
JournalInternational journal of radiation oncology, biology, physics
Volume7
Issue number1
DOIs
StatePublished - Jan 1981

Keywords

  • External radiation
  • Megavoltage
  • Prostatic cancer

ASJC Scopus subject areas

  • Radiation
  • Oncology
  • Radiology Nuclear Medicine and imaging
  • Cancer Research

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